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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE ACYL-COA DEHYDROGENASE FADE25
CommentsMb3302c, fadE25, len: 389 aa. Equivalent to Rv3274c, len: 389 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 389 aa overlap). Probable fadE25, Acyl-CoA Dehydrogenase (EC 1.3.99.-),equivalent to P46703|ACDP_MYCLE|FADE25|ACD|ML0737|B1308_F1_34 PROBABLE ACYL-COA DEHYDROGENASE FADE25 from Mycobacterium leprae (389 aa), FASTA scores: opt: 2394, E(): 3.8e-143, (92.05% identity in 389 aa overlap). Also similar to many e.g. Q9RIQ5|FADE FATTY ACID ACYL-COA DEHYDROGENASE from Streptomyces lividans (385 aa), FASTA scores: opt: 1692,E(): 4.9e-99, (67.35% identity in 383 aa overlap); P45867|ACDA_BACSU|ACD from Bacillus subtilis (379 aa),FASTA scores: opt: 1212, E(): 7.2e-69, (51.85% identity in 376 aa overlap); Q9K6D1|ACDA|BH3798 from Bacillus halodurans (380 aa), FASTA scores: opt: 1209, E(): 1.1e-68, (51.7% identity in 377 aa overlap); P52042|ACDS_CLOAB|BCD from Clostridium acetobutylicum (379 aa), FASTA scores: opt: 1056, E(): 4.6e-59, (44.6% identity in 379 aa overlap); etc. Contains PS00072 Acyl-CoA dehydrogenases signature 1, PS00073 Acyl-CoA dehydrogenases signature 2. BELONGS TO THE ACYL-COA DEHYDROGENASES FAMILY.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS36115083612677-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3302c|fadE25
MVGWAGNPSFDLFKLPEEHDEMRSAIRALAEKEIAPHAAEVDEKARFPEEALVALNSSGFNAVHIPEEYGGQGADSVATCIVIEEVARVDASASLIPAVNKLGTMGLILRGSEELKKQVLPALAAEGAMASYALSEREAGSDAASMRTRAKADGDHWILNGAKCWITNGGKSTWYTVMAVTDPDRGANGISAFMVHKDDEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIAYTKDRKQFGESISTFQAVQFMLADMAMKVEAARLMVYSAAARAERGEPDLGFISAASKCFASDVAMEVTTDAVQLFGGAGYTTDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR
      
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