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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CONSERVED TRANSMEMBRANE PROTEIN
CommentsMb3305, -, len: 271 aa. Equivalent to Rv3277, len: 271 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 271 aa overlap). Probable conserved transmembrane protein, equivalent, but longer 49 aa, to Q49673|B1308_C1_121|ML0734 PUTATIVE MEMBRANE PROTEIN from Mycobacterium leprae (228 aa), FASTA scores: opt: 1266,E(): 6.1e-78, (84.2% identity in 228 aa overlap). Also similar to various proteins (principally unknowns) e.g. Q9KZ84|SCE25.02 PUTATIVE INTEGRAL MEMBRANE PROTEIN from Streptomyces coelicolor (190 aa), FASTA scores: opt: 197,E(): 3.6e-06, (32.0% identity in 150 aa overlap); BAB50058|MLL3086 HYPOTHETICAL PROTEIN from Rhizobium loti (Mesorhizobium loti) (136 aa), FASTA scores: opt: 176,E(): 6.9e-05, (34.7% identity in 147 aa overlap); O29640|AF0615 HYPOTHETICAL PROTEIN from Archaeoglobus fulgidus (129 aa), FASTA scores: opt: 120, E(): 0.38,(23.35% identity in 120 aa overlap); Q9KJU8|GTCA TEICHOIC ACID GLYCOSYLATION PROTEIN from Listeria innocua (145 aa),FASTA scores: opt: 117, E(): 0.67, (23.85% identity in 151 aa overlap); etc. Equivalent to AAK47718 from Mycobacterium tuberculosis strain CDC1551 (256 aa) but longer 16 aa. Contains PS00044 Bacterial regulatory proteins, lysR family signature.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS36144663615284+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3305|Mb3305
MNEVTAGVRELATAIMVSRHLTGVLAGHGSQTVTYHFASILCSSVHSLVVSFADATIARLPGVVQPYAQRHHELIKFAIVGGTTFIIDTAIFYTLKLTVLEPKPVTAKVIAGIVAVIASYVLNREWSFRDRGGRERHHEALLFFAFSGVGVLLSMAPLWFSSYILQLRVPTVSLTMENIADFISAYIIGNLLQMAFRFWAFRRWVFPDEFARNPDKALESALTAGGIAEVFEDVLEGGFEDGNVTLLRAWRNRANRFAQLGDSSEPRVSKTL
      
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