Gene Mb3308
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE PROPIONYL-COA CARBOXYLASE BETA CHAIN 5 ACCD5 (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) |
| Comments | Mb3308, accD5, len: 548 aa. Equivalent to Rv3280,len: 548 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 548 aa overlap). Probable accD5,propyonyl-CoA carboxylase beta chain 5 (EC 6.4.1.3),equivalent to P53002|PCCB_MYCLE|ACCD5|ML0731|B1308_C1_125 PROBABLE PROPIONYL-COA CARBOXYLASE BETA CHAIN 5 from Mycobacterium leprae (549 aa), FASTA scores: opt: 3241,E(): 4e-192, (88.7% identity in 549 aa overlap). Also similar to many e.g. O87201|DTSR2 DTSR2 PROTEIN INVOLVED IN GLUTAMATE PRODUCTION from orynebacterium glutamicum (Brevibacterium flavum) (537 aa), FASTA scores: opt: 2604,E(): 6.9e-153, (74.1% identity in 529 aa overlap) (see first citation below); P53003|PCCB_SACER from Saccharopolyspora erythraea (Streptomyces erythraeus) (546 aa), FASTA scores: opt: 2466, E(): 2.2e-144, (70.2% identity in 530 aa overlap); O88155|DTSR1 DTSR1 PROTEIN from Corynebacterium glutamicum (Brevibacterium flavum) (543 aa), FASTA scores: opt: 2375, E(): 8.8e-139, (67.1% identity in 529 aa overlap (see citation below); Q9X4K7|PCCB from Streptomyces coelicolor (530 aa), FASTA scores: opt: 2360, E(): 7.3e-138, (67.9% identity in 533 aa overlap); O24789|MXPCCB from Myxococcus xanthus (524 aa), FASTA scores: opt: 1868, E(): 1.5e-107, (56.85% identity in 524 aa overlap); etc. Also similar with METHYLMALONYL-COA DECARBOXYLASES e.g. O59018|PH1287 from Pyrococcus horikoshii (522 aa), FASTA scores: opt: 1841,E(): 6.7e-106, (54.15% identity in 528 aa overlap). Also similarity with MTCY427.28 (43.8% identity in 434 aa overlap). BELONGS TO THE ACCD/PCCB FAMILY. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3616650 | 3618296 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3308|accD5
MTSVTDRSAHSAERSTEHTIDIHTTAGKLAELHKRREESLHPVGEDAVEKVHAKGKLTARERIYALLDEDSFVELDALAKHRSTNFNLGEKRPLGDGVVTGYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGINDGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPALTDFVIMVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHYAASGEQDAFDYVRELLSYLPPNNSTDAPRYQAAAPTGPIEENLTDEDLELDTLIPDSPNQPYDMHEVITRLLDDEFLEIQAGYAQNIVVGFGRIDGRPVGIVANQPTHFAGCLDINASEKAARFVRTCDCFNIPIVMLVDVPGFLPGTDQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSKDMGCDANLAWPTAQIAVMGASGAVGFVYRQQLAEAAANGEDIDKLRLRLQQEYEDTLVNPYVAAERGYVDAVIPPSHTRGYIGTALRLLERKIAQLPPKKHGNVPL
Bibliography
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