Gene Mb3324
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE ATP-DEPENDENT HELICASE LHR (LARGE HELICASE-RELATED PROTEIN) |
| Comments | Mb3324, lhr, len: 1513 aa. Equivalent to Rv3296,len: 1512 aa, from Mycobacterium tuberculosis strain H37Rv, (99.8% identity in 1512 aa overlap). Probable lhr,ATP-dependent helicase (EC 3.6.1.-), similar to others e.g. P30015|LHR_ECOLI|RHLF|B1653 from Escherichia coli stain K12 (1538 aa), FASTA scores: opt: 2930, E(): 1.5e-159, (47.55% identity in 1569 aa overlap); AAG56642|LHR from Escherichia coli stain O157:H7 EDL933 (1538 aa), FASTA scores: opt: 2930, E(): 1.5e-159, (47.6% identity in 1561 aa overlap); O86821|SC7C7.16c from Streptomyces coelicolor (1690 aa), FASTA scores: opt: 2919, E(): 7e-159, (53.55% identity in 1703 aa overlap); Q9HYW9|PA3272 from Pseudomonas aeruginosa (1448 aa), FASTA scores: opt: 907, E(): 6.2e-44, (35.85% identity in 1512 aa overlap); etc. SIMILAR TO DEAD/DEAH BOX HELICASE FAMILY AND TO HELICASE C-TERMINAL DOMAIN. Contains PS00017 ATP/GTP-binding site motif A and possible helix-turn-helix motif. |
| Functional category | Information pathways |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3631300 | 3635841 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3324|lhr
MRFAQPSALSRFSALTRDWFTSTFAAPTAAQASAWAAIADGDNTLVIAPTGSGKTLAAFLWALDSLAGSEPMSERPAATRVLYVSPLKALAVDVERNLRTPLAGLTRLAERQGLPAPQIRVGVRSGDTPPALRRQLVSQPPDVLITTPESLFLMLTSAARQTLTGVQTVIIDEIHAIAATKRGAHLALSLERLDDLSSRRRAQRIGLSATVRPPEELARFLSGQSPTTIVAPPAAKTVELSVQVPVPDMANLTDNTIWPDVEARLVDLIESHNSTIVFANSRRLAERLTARLNEIHAARCGIELAPDTNQQVAGGAPAHIMGSGQTFGAPPVLARAHHGSISKEQRAVVEEDLKRGQLKAVVATSSLELGIDMGAVDLVIQVQAPPSVASGLQRIGRAGHQVGEISRGVLFPKHRTDLLGCAVSVQRMLAGEIETMRVPANPLDILAQHTVAAAALEPLDADAWFDTVRRAAPFATLPRSLFEATLDLLSGKYPSTEFAELRPRLVYDRDTGTLTARPGAQRLAVTSGGAIPDRGLFAVYLATERPSRVGELDEEMVYESRPGDVISLGATSWRITEITHDRVLVIPAPGQPARLPFWRGDDAGRPAELGAALGALTGELAALDRTAFGTRCAGLGFDDYATDNLWRLLDDQRTATAVVPTDSTLLVERFRDELGDWRVILHSPYGLRVHGPLALAVGRRLRDRYGIDEKPTASDNGIMVRLPDTVSAGEDSPPGAELFVFDADEIDPIVTTEVAGSALFASRFRESAARALLLPRRHPGRRSPLWQQRQRAARLLEVARKYPDFPIVLETVRECLQNVYDVPILVELMARIAQRRVRVAEAETAKPSPFAASLLFGYVGAFMYEGDTPLAERRAAALALDGTLLAELLGRVELRELLDPDVIAATSRQLQHLAADRVARDAEGVADLLRLLGPLTEDEIAARAGAPEVSGWLDGLRAAKRALVVSFAGRSWWVAVEDMGRLRDGVGAAVPVGLPASFTEAVADPLGELLGRYARTHTPFTTAAAAARFGLGLRVTADVLGRLASDGRLVRGEFVAAAEGSAGGEQWCDAEVLRILRRRSLAALRAQAEPVSTAAYGRFLPAWQHVSAGNSGIDGLAAVIDQLAGVRIPASAIEPLVLAPRIRDYSPAMLDELLASGDVTWSGAGSISGSDGWIALHPADSAPMTLAEPAEIDFTDAHRAILASLGTGGAYFFRQLTHDGLTEAELKAALWELIWAGRVTGDTFAPVRAVLGGAGTRKRAAPAHGGHRPPRLSRYRLTHAQARNADPTVAGRWSALPLPEPDSTLRAHYQAELLLNRHGVLTKDAVAAEGVAGGFATLYKVLSAFEDAGRCQRGYFIESLGGAQFAVASTVDRLRSYLDGVDPEQPDYHAVVLAAADPANPYGAALPWPASSADGTARPGRKAGALVVLVDGELAWFLERGGRSLLTFTDDPEANHAAAIGLADLVTAGRVASILVERADGMPVLQPGGRASAALTALLAAGFVRTPRGLRRR
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