Gene Mb3337c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameupp
Gene length717 bp
IdentifierMb3337c
Location 3650995 bp
Protein summary information
Molecular mass25413.1 Da
Isoelectric point5.0606
Protein length238 amino acids
Cross-references
UniProtKB/TrEMBLX2BN45, P0A659
SWISS-MODELP0A659
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE URACIL PHOSPHORIBOSYLTRANSFERASE UPP (UMP PYROPHOSPHORYLASE) (UPRTASE) (UMP DIPHOSPHORYLASE)
CommentsMb3337c, upp, len: 238 aa. Equivalent to Rv3309c,len: 207 aa, from Mycobacterium tuberculosis strain H37Rv,with 5' extension identified by de novo proteomics of Mycobacterium tuberculosis strain H37Rv under exponential conditions. (See Schubert et al., 2013). Probable upp,uracil phosphoribosyltransferase (EC 2.4.2.9). Also similar to others e.g. P36399|UPP_STRSL from Streptococcus salivarius (209 aa),Q9A194|UPP|SPY0392 from Streptococcus pyogenes (209 aa), Q9RE01|UPP from Lactobacillus plantarum (209 aa), etc. BELONGS TO THE UPRTASE FAMILY. Mb3337c transcript and transcriptional start site identified in Mycobacterium bovis strain AF2122/97 grown under exponential conditions.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS36509953651711-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3337c|upp
MDGVDRSRGWTHPYQPPFRGPSHDCYIGFNAVQVHVVDHPLAAARLTTLRDERTDNAGFRAALRELTLLLIYEATRDAPCEPVPIRTPLAETVGSRLTKPPLLVPVLRAGLGMVDEAHAALPEAHVGFVGVARDEQTHQPVPYLDSLPDDLTDVPVMVLDPMVATGGSMTHTLGLLISRGAADITVLCVVAAPEGIAALQKAAPNVRLFTAAIDEGLNEVAYIVPGLGDAGDRQFGPR
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