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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE NAGA (GLCNAC 6-P DEACETYLASE)
CommentsMb3365, nagA, len: 383 aa. Equivalent to Rv3332,len: 383 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 383 aa overlap). Probable nagA,N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25),similar to many e.g. Q9KXV7|SCD95A.17c PUTATIVE DEACETYLASE from Streptomyces coelicolor (381 aa), FASTA scores: opt: 1090, E(): 1.6e-55, (47.8% identity in 385 aa overlap); Q9PDB4|XF1465 N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE from Xylella fastidiosa (386 aa), FASTA scores: opt: 667, E(): 3.5e-31, (38.3% identity in 394 aa overlap); Q9AAZ9|CC0443 N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE from Caulobacter crescentus (378 aa), FASTA scores: opt: 661, E(): 7.5e-31, (38.9% identity in 383 aa overlap); O34450||NAGA_BACSU N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE from Bacillus subtilis (396 aa), FASTA scores: opt: 571, E(): 1.2e-25,(32.45% identity in 376 aa overlap); etc. Equivalent to AAK47778 from Mycobacterium tuberculosis strain CDC1551 (346 aa) but longer 37 aa. BELONGS TO THE NAGA FAMILY.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS36758443676995+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3365|nagA
MTVLGADAVVIDGRICRPGWVHTADGRILSGGAGAPPMPADAEFPDAIVVPGFVDMHVHGGGGASFADGNAADIARAAEFHLRHGTTTTLASLVTAGPAELLSAVGALAEATRDGVVAGIHLEGPWLSPARCGAHDHTRMRAPDPAEIESVLAAADGAVRMVTLAPELPGSDAAIRRFRDAEVVVAVGHTDATYTQTRHAIDLGATVGTHLFNAMPPLDHRAPGPVLALLCDPRVTVEIIADGVHVHPAVVHAVIEAVGPDRVAVVTDAIAAAGCGDGAFRLGTMPIEVESSVARVAGASTLAGSTTTMDQLFRTVAGLGSKSDSAGDVALAAAVQVTSATPARALGLTGVGRLAAGYAANLVVLDRDLRVTAVMVNDDWRVG
      
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