Gene Mb3373
in Mycobacterium bovis AF2122/97
General annotation
Type | CDS |
Function | Unknown |
Product | PROBABLE HOMOSERINE O-ACETYLTRANSFERASE META (HOMOSERINE O-TRANS-ACETYLASE) (HOMOSERINE TRANSACETYLASE) (HTA) |
Comments | Mb3373, metA, len: 379 aa. Equivalent to Rv3341,len: 379 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 379 aa overlap). Probable metA,homoserine o-acetyltransferase (EC 2.3.1.31), equivalent to O32874|METX_MYCLE|META|ML0682|MLCB1779.11 HOMOSERINE O-ACETYLTRANSFERASE from Mycobacterium leprae (382 aa),FASTA scores: opt: 2263, E(): 9.2e-129, (85.0% identity in 380 aa overlap). Also highly similar to many e.g. O68640|METX_CORGL|META from Corynebacterium glutamicum (Brevibacterium flavum) (379 aa), FASTA scores: opt: 1135,E(): 5.9e-61, (48.5% identity in 371 aa overlap); Q9AAS1|CC0525 from Caulobacter crescentus (382 aa), FASTA scores: opt: 860, E(): 2e-44, (40.5% identity in 363 aa overlap); P94891|METX_LEPME from Leptospira meyeri (379 aa), FASTA scores: opt: 787, E(): 4.9e-40, (38.2% identity in 385 aa overlap); etc. BELONGS TO THE AB HYDROLASE FAMILY, HTA SUBFAMILY. |
Functional category | Intermediary metabolism and respiration |
Mutant | Check for mutants available at TARGET website |
Coordinates
Type | Start | End | Orientation |
---|---|---|---|
CDS | 3684738 | 3685877 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3373|metA MTISDVPTQTLPAEGEIGLIDVGSLQLESGAVIDDVCIAVQRWGKLSPARDNVVVVLHALTGDSHITGPAGPGHPTPGWWDGVAGPGAPIDTTRWCAVATNVLGGCRGSTGPSSLARDGKPWGSRFPLISIRDQVQADVAALAALGITEVAAVVGGSMGGARALEWVVGYPDRVRAGLLLAVGARATADQIGTQTTQIAAIKADPDWQSGDYHETGRAPDAGLRLARRFAHLTYRGEIELDTRFANHNQGNEDPTAGGRYAVQSYLEHQGDKLLSRFDAGSYVILTEALNSHDVGRGRGGVSAALRACPVPVVVGGITSDRLYPLRLQQELADLLPGCAGLRVVESVYGHDGFLVETEAVGELIRQTLGLADREGACRR
Bibliography
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