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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE METHYLTRANSFERASE (METHYLASE)
CommentsMb3374, -, len: 243 aa. Equivalent to Rv3342, len: 243 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 243 aa overlap). Possible methyltransferase (EC 2.1.1.-), similar to various proteins e.g. Q9I5X8|PA0558 HYPOTHETICAL PROTEIN from Pseudomonas aeruginosa (255 aa), FASTA scores: opt: 496,E(): 4.4e-24, (39.85% identity in 236 aa overlap); Q9XBC9|CZA382.22c PUTATIVE RRNA METHYLASE from Amycolatopsis orientalis (259 aa), FASTA scores: opt: 473,E(): 1.2e-22, (42.45% identity in 245 aa overlap); Q9UTA8|SPAC25B8.10 PUTATIVE METHYLTRANSFERASE from Schizosaccharomyces pombe (Fission yeast) (256 aa), FASTA scores: opt: 470, E(): 1.9e-22, (35.7% identity in 238 aa overlap); and Q9UTA9|SPAC25B8.09 PUTATIVE METHYLTRANSFERASE from Schizosaccharomyces pombe (Fission yeast) (251 aa), FASTA scores: opt: 418, E(): 3.4e-19,(31.2% identity in 237 aa overlap); etc. Start uncertain. BELONGS TO THE METHYLTRANSFERASE SUPERFAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS36858743686605+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3374|Mb3374
MTCSRRDMSLSFGSAVGAYERGRPSYPPEAIDWLLPAAARRVLDLGAGTGKLTTRLVERGLDVVAVDPIPEMLDVLRAALPQTVALLGTAEEIPLDDNSVDAVLVAQAWHWVDPARAIPEVARVLRPGGRLGLVWNTRDERLGWVRELGEIIGRDGDPVRDRVTLPEPFTTVQRHQVEWTNYLTPQALIDLVASRSYCITSPAQVRTKTLDRVRQLLATHPALANSNGLALPYVTVCVRATLA
      
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