Gene Mb3377c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PE-PGRS FAMILY PROTEIN [FIRST PART] |
| Comments | Mb3377c, PE_PGRS50a, len: 539 aa. Equivalent to 5' end of Rv3345c, len: 1538 aa, from Mycobacterium tuberculosis strain H37Rv, (88.25% identity in 315 aa overlap). Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins. Similar to AAK47791 from strain CDC1551 but with some big gaps (after residues 501 and 1419; and for AAK47791 after residue 991). Similar to many from Mycobacterium tuberculosis strains H37Rv and CDC1551 e.g. O53559|Rv3514|MTV023.21 (1489 aa), FASTA scores: opt: 4508, E(): 7e-161, (52.1% identity in 1529 aa overlap); MTV004_1, MTV023_21,MTV023_15, MTCY493_4, MTV039_16, MTV008_46, MTV023_14,MTV023_19, MTV043_26, MTCY493_2, MTCY441_4; etc. REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis strain H37Rv, PE_PGRS50 exists as a single gene. In Mycobacterium bovis, a single base deletion (g-*) splits PE_PGRS50 into 2 parts, PE_PGRS50a and PE_PGRS50b. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3694689 | 3696308 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3377c|PE_PGRS50a
MVMSLMVAPELVAAAAADLTGIGQAISAANAAAAGPTTQVLAAAGDEVSAAIAALFGTHAQEYQALSARVATFHEQFVRSLTAAGSAYATAEAANASPLQALEQQVLGAINAPTQLWLGRPLIGDGVHGAPGTGQPGGAGGLLWGNGGNGGSGAAGQVGGPGGAAGLFGNGGSGGSGGAGAAGGVGGSGGWLNGNGGAGGAGGTGANGGAGGNAWLFGAGGSGGAGTNGGVGGSGGFVYGNGGAGGIGGIGGIGGNGGDAGLFGNGGAGGPGPRACRVPPASTAATAATAATAEPAATAGAAGYWLATAGPAGPAASAATVVRAALAIRVSPSTTVPAVTAVTAATPAWAGPVGPAACWRVRTVPPAPPPPAAATAAMAASAPPPTHPYKPAGPAVMAVMAGWSATAAPAAPAVPVMRVPPALPVPPYNRRAVTAPMAAPGATAVMAEMAAPSTATAASAARAVPAVAAAPAETDSTPPPWVRPVPMAVWAATAARAVTAVVAAPAAPRSPAPPARPGTAAPAVTAARPVMAEPVPPVM
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