Gene Mb3385c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PPE FAMILY PROTEIN [FIRST PART] |
| Comments | Mb3385c, PPE56a, len: 434 aa. Equivalent to 5' end of Rv3350c, len: 3716 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 434 aa overlap). Member of the Mycobacterium tuberculosis PPE family of Gly-,Ala-, Asn-rich proteins, similar to many Mycobacterium tuberculosis proteins from strains H37Rv and CDC1551, e.g. O50378|Rv3347c|MTV004.03c (3157 aa), FASTA scores: opt: 6497, E(): 0, (61.65% identity in 3756 aa overlap); MTCY28_16, MTV050_2, MTY13E10_17, MTCY63_10, MTCY180_1,MTCY63_9, MTV050_1, MTV014_3, MTY13E10_15; etc. REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis strain H37Rv, PPE56 exists as a single gene. In Mycobacterium bovis, 2 frameshifts due to single base transversion (c-a) and a single base deletion (g-*) splits PPE56 into 3 parts, PPE56a, PPE56b and PPE56d. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3719324 | 3720628 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3385c|PPE56a
MEFPVLPPEINSVLMYSGAGSSPLLAAAAAWDGLAEELGSAAVSFGQVTSGLTAGVWQGAAAAAMAAAAAPYAGWLGSVAAAAEAVAGQARVVVGVFEAALAATVDPALVAANRARLVALAVSNLLGQNTPAIAAAEAEYELMWAADVAAMAGYHSGASAAAAALPAFSPPAQALGGGVGAFLTALFASPAKALSLNAGLGNVGNYNVGLGNVGVFNLGAGNVGGQNLGFGNAGGTNVGFGNLGNGNVGFGNSGLGAGLAGLGNIGLGNAGSSNYGFANLGVGNIGFGNTGTNNVGVGLTGNHLTGIGGLNSGTGNIGLFNSGTGNVGFFNSGTGNFGVFNSGNYNTGVGNAGTASTGLFNAGNFNTGVVNVGSYNTGSFNAGDTNTGGFNPGGVNTGWLNTGNTNTGIANSGNVNTGAFISGNFNNGVLWVGD
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