Gene Mb3449c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb3449c
Gene length828 bp
IdentifierMb3449c
Location 3786322 bp
Protein summary information
Molecular mass28659.0 Da
Isoelectric point9.965
Protein length275 amino acids
Orthologues
M. tuberculosisRv3415c
Cross-references
UniProtKB/TrEMBLQ7TWJ3
SWISS-MODELA0A1R3Y441
General annotation
TypeCDS
FunctionUnknown
ProductCONSERVED HYPOTHETICAL PROTEIN
CommentsMb3449c, -, len: 275 aa. Equivalent to Rv3415c,len: 275 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 275 aa overlap). Conserved hypothetical protein, equivalent to Q9CCV3|ML0383 HYPOTHETICAL PROTEIN from Mycobacterium leprae (281 aa),FASTA scores: opt: 1278, E(): 4.2e-71, (73.5% identity in 279 aa overlap); and Q49858|B229_C1_175 HYPOTHETICAL 27.4 KDA PROTEIN from Mycobacterium leprae (264 aa), FASTA scores: opt: 1186, E(): 1.7e-65, (74.05% identity in 258 aa overlap). And C-terminus highly similar to N-terminal part of Q49726|B1620_C3_232 HYPOTHETICAL 12.9 KDA PROTEIN from Mycobacterium leprae (122 aa), FASTA scores: opt: 580, E(): 1.1e-28, (74.6% identity in 126 aa overlap). Also some similarity with P71677|RIBD_MYCTU|RIBG|Rv1409|MT1453|MTCY21B4.26 RIBOFLAVIN BIOSYNTHESIS PROTEIN R (339 aa), FASTA scores: opt: 143, E(): 0.13, (28.25% identity in 184 aa overlap).
Functional categoryConserved hypotheticals
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS37863223787149-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3449c|Mb3449c
MNETPHAPVVEQVLVAAAFGNQPGSWPLPTAITPHHLWLRAVAAGGQGRYAHAYGDLSVLRRLVPAGPLASLAHSTQGSLLRQLGWHTLARGWDGRALALAGADREAGADALIGLAADALGVGRFAAAGALLDRADPLVVSPLVADRLAVRRRWVAAELAMATGDGATAVRHAEEAVELTQAMAVASARHRVKSDVVLAAALCSAGAVARARAVGEEALDATARFGLLPLRWALACLLIDIGTVTFSAQQLRELTKIRNICAGQVRRAGGCWRTA
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