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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productesx conserved component eccd4. esx-4 type vii secretion system protein. probable integral membrane protein.
CommentsMb3478, -, len: 467 aa. Equivalent to Rv3448, len: 467 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 467 aa overlap). Probable conserved integral membrane protein, showing some similarity with Q9CD35|ML2529 from Mycobacterium leprae (485 aa), FASTA scores: opt: 371, E(): 3.6e-14, (27.25% identity in 481 aa overlap); and two proteins from Mycobacterium tuberculosis O86362|Rv0290|MTV035.18 (472 aa), FASTA scores: opt: 429,E(): 1.6e-17, (28.6% identity in 479 aa overlap); and O05457|Rv3887c|MTCY15F10.25 (509 aa), FASTA scores: opt: 203, E(): 0.00019, (25.6% identity in 492 aa overlap). Contains PS00402 Binding-protein-dependent transport systems inner membrane comp signature.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS38160533817456+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3478|eccd4
MPTSDPGLRRVTVHAGAQAVDLTLPAAVPVATLIPSIVDILGDRGASPATAARYQLSALGAPALPNATTLAQCGIRDGAVLVLHKSSAQPPTPRCDDVAEAVAAALDTTARPQCQRTTRLSGALAASCITAGGGLMLVRNALGTNVTRYSDATAGVVAAAGLAALLFAVIACRTYRDPIAGLTLSVIATIFGAVAGLLAVPGVPGVHSVLVAAMAAAATSVLAMRITGCGGITLTAVACCAVVVAAATLVGAITAAPVPAIGSLDTLASFGLLEVSARMAVLLAGLSPRLPPALNPDDADALPTTDRLTTRANRADAWLTSLLAAFAASATIGAIGTAVATHGIHRSSMGGIALAAVTGALLLLRARSADTRRSLVFAICGITTVATAFTVAADRALEHGPWIAALTAMLAAVAMFLGFVAPALSLSPVTYRTIELLECLALIAMVPLTAWLCGAYSAVRHLDLTWT
      
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