Gene Mb3527c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemce4C
Gene length1074 bp
IdentifierMb3527c
Location 3861506 bp
Protein summary information
Molecular mass38150.5 Da
Isoelectric point9.4511
Protein length357 amino acids
Cross-references
InterProIPR003399, IPR005693, IPR008360
UniProtKB/TrEMBLQ7TWD4
SWISS-MODELA0A1R3Y4C5
General annotation
TypeCDS
FunctionUnknown
ProductMCE-FAMILY PROTEIN MCE4C
CommentsMb3527c, mce4C, len: 357 aa. Equivalent to Rv3497c,len: 357 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 357 aa overlap). mce4C; belongs to 24-membered Mycobacterium tuberculosis Mce protein family (see citations below for more information), highly similar to Mycobacterium tuberculosis proteins O07415|R0171|MTCI28.11|mce1C (515 aa); O07787|Rv0591|MTCY19H5.31|mce2C (481 aa); and O53969|Rv1968|MTV051.06|mce3C (410 aa). Also similar to others e.g. Q9F358|SC8A2.05c PUTATIVE SECRETED PROTEIN from Streptomyces coelicolor (351 aa), FASTA scores: opt: 658, E(): 1.1e-30, (33.95% identity in 318 aa overlap); Q9CD12|MCE1C|ML2591 PUTATIVE SECRETED PROTEIN from Mycobacterium leprae (519 aa), FASTA scores: opt: 555,E(): 1.2e-24, (28.35% identity in 328 aa overlap); etc. Hydrophobic region at N-terminus.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS38615063862579-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3527c|mce4C
MLNRKPSSKHERDPLRTGIFGLVLVICVVLIAFGYSGLPFWPQGKTYDAYFTDAGGITPGNSVYVSGLKVGAVSAVSLAGNSAKVTFSVDRSIVVGDQSLAAIRTDTILGERSIAVSPAGSGKSTTIPLSRTTTPYTLNGVLQDLGRNANDLNRPQFEQALNVFTQALHDATPQVRGAVDGLTSLSRALNRRDEALQGLLAHAKSVTSVLSERAEQVNKLVEDGNQLFAALDARRAALSALISGIDDVAAQISGFVADNRKEFGPALSKLNLVLANLNERRDYITEALKRLPTYATTLGEVVGSGPGFNVNVYSVLPGPLVATVFDLVFQPGKLPDSLADYLRGFIQERWIIRPKSP
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