Gene Mb3528c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemce4B
Gene length1053 bp
IdentifierMb3528c
Location 3862569 bp
Protein summary information
Molecular mass36880.3 Da
Isoelectric point8.2023
Protein length350 amino acids
Cross-references
InterProIPR003399, IPR005693
UniProtKB/TrEMBLQ7TWD3
SWISS-MODELA0A1R3Y606
General annotation
TypeCDS
FunctionUnknown
ProductMCE-FAMILY PROTEIN MCE4B
CommentsMb3528c, mce4B, len: 350 aa. Equivalent to Rv3498c,len: 350 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 350 aa overlap). mce4B; belongs to 24-membered Mycobacterium tuberculosis Mce protein family (see citations below for more information), highly similar to Mycobacterium tuberculosis proteins O07414|Rv0170|MTCI28.10|mce1B (346 aa); O07788|Rv0590|MTCY19H5.32c|mce2B (275 aa); and O53968|Rv1967|MTV051.05|mce3B (342 aa). Also similar to others e.g. Q9CD13|MCE1B|ML2590 PUTATIVE SECRETED PROTEIN from Mycobacterium leprae (346 aa), FASTA scores: opt: 803, E(): 6.1e-41, (41.05% identity in 346 aa overlap); Q9F357|SC8A2.06c PUTATIVE SECRETED PROTEIN from Streptomyces coelicolor (354 aa), FASTA scores: opt: 624,E(): 3.4e-30, (32.55% identity in 338 aa overlap); etc. Hydrophobic region at N-terminus.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS38625693863621-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3528c|mce4B
MAGSGVPSHRSMVIKVSVFAVVMLLVAAGLVVVFGDFRFGPTTVYHATFTDASRLKAGQKVRIAGVPVGSVKAVKLNPDHSIDVAFAIDRSYTLYSSTRAVIRYENLVGDRFLEITSGPGELRKLPPGGTINVAHTQPALDLDALLGGLRPVLKGFDADKINTITSAVIELLQGQGGPLANVLADTGAFSAALGARDQLIGEVITNLNAVLATVDAKSAQFSASVDQLQQLVSGLAKNRDPIAGAISPLASTTTDLTELLRNSRRPLQGILENARPLATELDNRKAEVNNDIEQLGEDYLRLSALGSYGAFFNIYFCSVTIKINGPAGSDILLPIGGQPDPSKGRCAFAK
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