Gene Mb3531c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameyrbE4A
Gene length765 bp
IdentifierMb3531c
Location 3865720 bp
Protein summary information
Molecular mass26639.7 Da
Isoelectric point8.9903
Protein length254 amino acids
Orthologues
M. tuberculosisRv3501c
Cross-references
InterProIPR003453
UniProtKB/TrEMBLQ7TWD0
SWISS-MODELA0A1R3Y4H4
General annotation
TypeCDS
FunctionUnknown
Productconserved integral membrane protein yrbe4a. possible abc transporter.
CommentsMb3531c, yrbE4A, len: 254 aa. Equivalent to Rv3501c, len: 254 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 254 aa overlap). yrbE4A,hypothetical unknown integral membrane protein, part of mce4 operon and member of YrbE family (see citations below for more information), highly similar to Mycobacterium tuberculosis proteins O07412|Rv0167|MTCI28.07|yrbE1A (265 aa); O07791|Rv0587|MTCY19H5.35|yrbE2A (265 aa); and O53965|Rv1964|MTV051.02|yrbE3A (265 aa). Also highly similar to conserved hypothetical integral membrane proteins of the P45030|YRBE_HAEIN (261 aa) type, e.g. Q9CD16|YRBE1A|ML2587 from Mycobacterium leprae (267 aa),FASTA scores: opt: 1059, E(): 1e-57, (64.75% identity in 247 aa overlap); P45030|YRBE_HAEIN|HI1086 from Haemophilus influenzae (261 aa), FASTA scores: opt: 313, E(): 3e-14,(25.7% identity in 241 aa overlap); etc.
Functional categoryVirulence, detoxification, adaptation
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS38657203866484-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3531c|yrbE4A
MIQQLAVPARAVGGFFEMSMDTARAAFRRPFQFREFLDQTWMVARVSLVPTLLVSIPFTVLVAFTLNILLREIGAADLSGAGTAFGTITQLGPVVTVLVVAGAGATAICADLGARTIREEIDAMRVLGIDPIQRLVVPRVLASTLVALLLNGLVCAIGLSGGYAFSVFLQGVNPGAFINGLTVLTGLRELILAEIKALLFGVMAGLVGCYRGLTVKGGPKGVGNAVNETVVYAFICLFVINVVMTAIGVRISAQ
Bibliography
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