Gene Mb3553 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameltp3
Gene length1185 bp
IdentifierMb3553
Location 3902744 bp
Protein summary information
Molecular mass41421.3 Da
Isoelectric point6.6355
Protein length394 amino acids
Orthologues
M. tuberculosisRv3523
Cross-references
InterProIPR002155, IPR016038, IPR016039
UniProtKB/TrEMBLQ7TWA8
SWISS-MODELA0A1R3Y4D8
General annotation
TypeCDS
FunctionUnknown
Productprobable lipid carrier protein or keto acyl-coa thiolase ltp3
CommentsMb3553, -, len: 394 aa. Equivalent to Rv3523, len: 394 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 394 aa overlap). Probable lipid carrier protein or keto acyl-CoA thiolase (EC 2.3.1.16),similar to several e.g. O30037|AF0202 3-KETOACYL-COA THIOLASE (ACAB-6) from Archaeoglobus fulgidus (380 aa) FASTA scores: opt: 782, E(): 1.7e-40, (38.35% identity in 386 aa overlap); Q9Y9A1|APE2384 LONG HYPOTHETICAL NON SPECIFIC LIPID-TRANSFER PROTEIN (ACETHYL CoA SYNTHETASE) (EC 6.2.1.-) from Aeropyrum pernix (394 aa), FASTA scores: opt: 626, E(): 5.9e-31, (35.75% identity in 386 aa overlap); BAB59210|TVG0067506 LIPID TRANSFER PROTEIN from Thermoplasma volcanium (390 aa), FASTA scores: opt: 591,E(): 8.1e-29, (34.35% identity in 384 aa overlap); Q9YDI4|APE0929 LONG HYPOTHETICAL NONSPECIFIC LIPID-TRANSFER PROTEIN from Aeropyrum pernix (400 aa) FASTA scores: opt: 588, E(): 1.3e-28, (31.6% identity in 408 aa overlap); O30104|AF0133 3-KETOACYL-COA THIOLASE (ACAB-3) from Archaeoglobus fulgidus (411 aa) FASTA scores: opt: 583, E(): 2.6e-28, (39.8% identity in 412 aa overlap); O29811|AF0438 3-KETOACYL-COA THIOLASE (ACAB-8) from Archaeoglobus fulgidus (387 aa), FASTA scores: opt: 574, E(): 8.8e-28, (30.95% identity in 388 aa overlap); etc.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS39027443903928+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3553|ltp3
MAGKLAAVLGTGQTKYVAKRQDVSMNGLVREAIDRALADSGSTFDDIDAVVVGKAPDFFEGVMMPELFMADAMGATGKPLIRVHTAGSVGGSTGVVAASLVQSGKYRRVLALAWEKQSESNAMWALSIPVPFTKPVGAGAGGYFAPHVRAYIRRSGAPAHIGAMVAVKDRLNGSRNPLAHLQQPDITLEKVMASQMLWDPIRFDETCPSSDGACAVVVGDEEIADARLAQGHPVAWIHGTALRTEPLAFAGRDQVNPQAGRDAAAALWKAAGITSPIDEIDAAEIYVPFSWFEPMWLENLGFAREGEGWKLTEAGETAIGGRLPVNPSGGVLSANPIGASGLIRFAEAAIQVMGKAEARQVPGARKALGHAYGGGSQYFSMWVVGCEKPKQAAA
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