Gene Mb3579c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE |
| Comments | Mb3579c, -, len: 259 aa. Equivalent to Rv3549c,len: 259 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 259 aa overlap). Probable short-chain dehydrogenase/reductase (EC 1.-.-.-), similar to various dehydrogenases/reductases (generally belong to the SDR FAMILY) e.g. Q9UKU3 from Homo sapiens (Human) (270 aa),FASTA scores: opt: 451, E(): 4.8e-21, (38.05% identity in 247 aa overlap); Q9S274|SCI28.09c from Streptomyces coelicolor (234 aa), FASTA scores: opt: 439, E(): 2.4e-20,(36.8% identity in 231 aa overlap); Q9PFI6|XF0671 from Xylella fastidiosa (247 aa), FASTA scores: opt: 437, E(): 3.4e-20, (37.7% identity in 252 aa overlap); etc. Also highly similar to O33308|FABG5|Rv2766c|MTV002.31c ALCOHOL DEHYDROGENASE (SDR FAMILY) from Mycobacterium tuberculosis (260 aa), FASTA scores: opt: 504, E(): 2.3e-24, (38.5% identity in 244 aa overlap). Contains PS00061 Short-chain alcohol dehydrogenase family signature. BELONGS TO THE SHORT-CHAIN DEHYDROGENASES/REDUCTASES (SDR) FAMILY. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3931534 | 3932313 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3579c|Mb3579c
MTLAEAADAINFGLAGRVVLVTGGVRGVGAGISSVFAEQGATVITCARRAVDGQPYEFHRCDIRDEDSVKRLVGEIGERHGRLDMLVNNAGGSPYALAAEATHNFHRKIVELNVLAPLLVSQHANVLMQAQPNGGSIVNICSVSGRRPTPGTAAYGAAKAGLENLTTTLAVEWAPKVRVNAVVVGMVETERSELFYGDAESIARVAATVPLGRLARPADIGWAAAFLASDAASYISGATLEVHGGGEPPPYLGASSANK
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