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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productconserved protein
CommentsMb3585c, -, len: 289 aa. Equivalent to Rv3555c,len: 289 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 289 aa overlap). Hypothetical protein,highly similar to others from Mycobacterium tuberculosis e.g. O53562|AL022022|Rv3517|MTV023.24 (279 aa), FASTA scores: opt: 874, E(): 8.3e-48, (49.45% identity in 275 aa overlap); P71763|Rv1482c|MTCY277.03c (339 aa), FASTA scores: opt: 755, E(): 3e-40, (45.75% identity in 260 aa overlap); O69681|Rv3714c|MTV025.062c (296 aa), FASTA scores: opt: 733, E(): 6.4e-39, (44.1% identity in 281 aa overlap); etc. Also highly similar to other mycobacterial hypothetical proteins e.g. O07396|MAV346 from M. avium (346 aa), FASTA scores: opt: 714, E(): 1.1e-37, (44.6% identity in 260 aa overlap); and Q50134|U650AG|MLCB57.67c from Mycobacterium leprae (75 aa), FASTA scores: opt: 130,E(): 0.17, (35.1% identity in 57 aa overlap) (only partial homology with this protein). Shows some similarity to P52392|NHSR_STRAS PUTATIVE NOSIHEPTIDE RESISTANCE REGULATORY PROTEIN (ORF699) from Streptomyces actuosus (233 aa), FASTA scores: opt: 120, E(): 1.9, (25.25% identity in 194 aa overlap).
Functional categoryConserved hypotheticals
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS39380453938914-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3585c|Mb3585c
MDELPWPVLGSEVLAAKAIPERAMRQLYEPVYPGVYAPAGVELTARQRAHAAWLWSRRRAVVAGNSAAALLGAKWVNPALDAELVHANRKPPPRIVVHTDRLAPHETVAVDGVAVTTPARTAFDIGRRTPSRLQAVQRLDALANSTDVKVADVQAVIAEHTGARGLVRLRAVLPLIDGGAESPQETWTRLVLIDAGLPKPQTQIRVFDDYGDFVARIDLGYEQLRVGVEYDGPQHWTDPAQRARDIERSTALLDLGWTIIRVTSELLRYRRGTFVGRVDAAMRAAGWRP
      
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