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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductARYLAMINE N-ACETYLTRANSFERASE NAT (ARYLAMINE ACETYLASE)
CommentsMb3596c, nat, len: 283 aa. Equivalent to Rv3566c,len: 283 aa, from Mycobacterium tuberculosis H37Rv,(100.0% identity in 283 aa overlap). nat (alternate gene name: nhoA), arylamine N-acetyltransferase (EC 2.3.1.5) (see citation below), highly similar to O86309|NAT_MYCSM ARYLAMINE N-ACETYLTRANSFERASE from Mycobacterium smegmatis (see citation below) (275 aa), FASTA scores: opt: 1114,E(): 3e-66, (60.95% identity in 274 aa overlap). Also highly similar to others e.g. Q98D42|BAB51429|MLR4870 from Rhizobium loti (Mesorhizobium loti) (278 aa), FASTA scores: opt: 697, E(): 1.1e-38, (44.1% identity in 272 aa overlap); P77567|NHOA_ECOLI|B1463 from Escherichia coli strain K12 (281 aa), FASTA scores: opt: 537, E(): 4.4e-28,(38.85% identity in 273 aa overlap); Q00267|NHOA_SALTY from Salmonella typhimurium (281 aa), FASTA scores: opt: 507, E(): 4.3e-26, (34.8% identity in 273 aa overlap); etc. BELONGS TO THE ARYLAMINE N-ACETYLTRANSFERASE FAMILY. Note that previously known as nhoA (332 aa) and that nucleotide 4007874 has been changed since first submission (G deleted).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS39505463951397-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3596c|nat
MALDLTAYFDRINYRGATDPTLDVLQDLVTVHSRTIPFENLDPLLGVPVDDLSPQALADKLVLRRRGGYCFEHNGLMGYVLAELGYRVRRFAARVVWKLAPDAPLPPQTHTLLGVTFPGSGGCYLVDVGFGGQTPTSPLRLETGAVQPTTHEPYRLEDRVDGFVLQAMVRDTWQTLYEFTTQTRPQIDLKVASWYASTHPASKFVTGLTAAVITDDARWNLSGRDLAVHRAGGTEKIRLADAAAVVDTLSERFGINVADIGERGALETRIDELLARQPGADAP
      
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