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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productpossible oxidoreductase. possible 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione hydroxylase.
CommentsMb3601c, -, len: 394 aa. Equivalent to Rv3570c,len: 394 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 394 aa overlap). Possible oxidoreductase (EC 1.-.-.-), most similar to hydroxylases and oxygenases (and also some similarity to acyl-coa dehydrogenases) e.g. O69349 HYDROXYLASE from Rhodococcus erythropolis (393 aa), FASTA scores: opt: 958, E(): 1.1e-53, (39.95% identity in 383 aa overlap); P26698|PIGM_RHOSO PIGMENT PROTEIN from Rhodococcus sp. strain ATCC 21145 (387 aa), FASTA scores: opt: 665, E(): 5.4e-35, (32.2% identity in 382 aa overlap); Q9ZGA9|LANZ5 OXYGENASE HOMOLOG from Streptomyces cyanogenus (397 aa) FASTA scores: opt: 588, E(): 4.5e-30, (30.55% identity in 386 aa overlap); Q9F0J3|NCNH HYDROXYLASE from Streptomyces arenae (405 aa), FASTA scores: opt: 580, E(): 1.5e-29,(31.25% identity in 336 aa overlap); O69789|BPFA INDOLE DIOXYGENASE from Rhodococcus opacus (399 aa), FASTA scores: opt: 558, E(): 3.7e-28, (31.8% identity in 387 aa overlap); etc.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS39543013955485-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3601c|hsaa
MTSIQQRDAQSVLAAIDDLLPEIRDRAQATEDLRRLPDETVKALDDVGFFTLLQPQQWGGLQCDPALFFEATRRLASVCGSTGWVSSIVGVHNWHLALFDQRAQEEVWGEDPSTRISSSYAPMGAGVVVDGGYLVNGSWNWSSGCDHASWTFVGGPVIKDGRPVDFGSFLIPRSEYEIKDVWYVVGLRGTGSNTLVVKDVFVPRHRFLSYKAMNDHTAGGLATNSAPVYKMPWGTMHPTTISAPIVGMAYGAYAAHVEHQGKRVRAAFAGEKAKDDPFAKVRIAEAASDIDAAWRQLIGNVSDEYALLAAGKEIPFELRARARRDQVRATGRSIASIDRLFEASGATALSNEAPIQRFWRDAHAGRVHAANDPERAYVIFGNHEFGLPPGDTMV
      
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