Gene Mb3610c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | possible trna/rrna methyltransferase |
| Comments | Mb3610c, -, len: 402 aa. Equivalent to Rv3579c,len: 322 aa, from Mycobacterium tuberculosis strain H37Rv,(99.4% identity in 316 aa overlap). Putative tRNA/rRNA methyltransferase (EC 2.1.1.-), equivalent, but longer 31 aa, to Q9CCW4|ML0324 PUTATIVE METHYLTRANSFERASE from Mycobacterium leprae (278 aa), FASTA scores: opt: 1517,E(): 3.4e-79, (83.75% identity in 277 aa overlap). Also highly similar to Q9L0Q5|SCD8A.09 from Streptomyces coelicolor (314 aa), FASTA scores: opt: 937, E(): 3.4e-46,(56.75% identity in 319 aa overlap); and similar to others e.g. Q06753|YACO_BACSU from Bacillus subtilis (249 aa),FASTA scores: opt: 616, E(): 4.9e-28, (41.05% identity in 246 aa overlap); Q9KGF2|BH0113 from Bacillus halodurans (249 aa), FASTA scores: opt: 596, E(): 6.7e-27, (38.5% identity in 244 aa overlap); P74328|Y955_SYNY3|SLR0955 from Synechocystis sp. strain PCC 6803 (384 aa), FASTA scores: opt: 585, E(): 4e-26, (35.85% identity in 304 aa overlap); P39290|YJFH_ECOLI|B4180 from Escherichia coli strain K12 (243 aa), FASTA scores: opt: 521, E(): 1.2e-22,(38.1% identity in 244 aa overlap); etc. Equivalent to AAK48043 from Mycobacterium tuberculosis strain CDC1551 (253 aa) but longer 69 aa. POSSIBLY BELONGS TO THE RNA METHYLTRANSFERASE TRMH FAMILY. REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a single base insertion (*-g) leads to a longer product with a different COOH part compared to its homolog in Mycobacterium strain H37Rv (402 aa versus 322 aa). |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3964401 | 3965609 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3610c|Mb3610c
MPGNSRRRGAVRKSGTKKGAGVGSGGQRRRGLEGRGPTPPAHLRPHHPAAKRARAQPRRPVKRADETETVLGRNPVLECLRAGVPATALYVALGTEADERLTECVARAADSGIAIVELLRADLDRMTANHLHQGIALQVPPYNYAHPDDLLAAALDQPPALLVALDNLSDPRNLGAIMRSVAAFGGHGVLIPQRRSASVTAVAWRTSAGAAARIPVARATNLTRTLKGWADRGVRVIGLDAGGGTALDDVDGTDSLVVVVGSEGKGLSRLVRQNCDEVVSIPMAAQAESLNASVAAGVVLAAIARQRRRPREPREQDAESHDLSSNHAILRLLAPLRLDPQNLGAGPQREHRHRQGRRHGAQSQSGVLADAGVDVVPAQHAPPQQVRQRTGIGQVGSDVDPE
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