Gene Mb3626c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namePE_PGRS59
Gene length1479 bp
IdentifierMb3626c
Location 3979813 bp
Protein summary information
Molecular mass44636.8 Da
Isoelectric point6.251
Protein length492 amino acids
Cross-references
InterProIPR000084
UniProtKB/TrEMBLQ7TW43
SWISS-MODELA0A1R3Y4K4
General annotation
TypeCDS
FunctionUnknown
Productpe-pgrs family protein pe_pgrs59
CommentsMb3626c, PE_PGRS59, len: 492 aa. Equivalent to 5' end of Rv3595c, len: 439 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 257 aa overlap). Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins, similar to many e.g. O53439|Rv1091|MTV017.44 (853 aa), FASTA scores: opt: 1644, E(): 1.2e-57, (58.75% identity in 492 aa overlap). REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a single base deletion (a-*) and a 27 bp insertion (*-gcgcgccggggccaccgtttccgccgg), lead to a longer product with a different COOH part compared to its homolog in Mycobacterium tuberculosis (492 aa versus 439 aa).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS39798133981291-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3626c|PE_PGRS59
MSFVIAVPEFLSAAATDLANLGSTISAANAAASIPTTGVLAAGADDVSAAIAALFGAHAQAYQTISAQAATFHAQFVQTLSAGAGAYANAEAANVQQSLLNAINAPTQALLGRPLIGDGADGTAPGQNGGAGGLLYGNGGNGAAGVNAGIAGGSGGAAGLIGNGGSGGAGGAGAAGGSGGQGGLLYGNGGAGGNGGAATIPGGNGGAGGAGGNAWLFGNGGAGGLGAAGAAGAAGVNPLTVPAGQGSMGNNGEPGGPASQAPSSGKPVAPVALAVLACPLAGPAGPAETVAPARPAAPGGPAGPAALAVGVGSWSATAAQVASGAQGAKAASAPGAAPAVRAEWAAPGNQALGVTLVTGVTAGSAVTAAPAETAARAARAARAACSASPVAPGWAVPPVAGVMAGAVVSPVWPAPRALGLRAVAATATSASSALKVHPASPASRASPVDIVAAGPSAPRRLLEQLPSVTGPVEALARVEFCGQGVDLIAELG
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