Gene Mb3692c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb3692c
Gene length699 bp
IdentifierMb3692c
Location 4047130 bp
Protein summary information
Molecular mass23120.4 Da
Isoelectric point5.0793
Protein length232 amino acids
Orthologues
M. tuberculosisRv3668c
Cross-references
InterProIPR009003
UniProtKB/TrEMBLQ7TVZ6
SWISS-MODELA0A1R3Y4S1
General annotation
TypeCDS
FunctionUnknown
Productpossible protease
CommentsMb3692c, -, len: 232 aa. Equivalent to Rv3668c,len: 232 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 232 aa overlap). Possible protease (EC 3.4.-.-) (and more specifically a putative alkaline serine protease (EC 3.4.21.-), equivalent to Q9CB98|ML2295 HYPOTHETICAL PROTEIN from Mycobacterium leprae (234 aa),FASTA scores: opt: 1249, E(): 7.4e-66, (77.5% identity in 231 aa overlap). Also similar at C-terminal end with many proteases e.g. O86984 ALKALINE SERINE PROTEASE PRECURSOR from Thermomonospora fusca (368 aa), FASTA scores: opt: 190, E(): 0.00056, (28.9% identity in 173 aa overlap); Q55353|SAPII ALKALINE SERINE PROTEASE II from Streptomyces sp (382 aa), FASTA scores: opt: 160, E(): 0.032, (27.15% identity in 199 aa overlap); O54109|SC10A5.18 PUTATIVE SECRETED PROTEASE from Streptomyces coelicolor (411 aa),FASTA scores: opt: 155, E(): 0.066, (26.4% identity in 163 aa overlap); Q54392|SAL|SCI11.35C SERINE PROTEASE SAL PRECURSOR (300 aa), FASTA scores: opt: 153, E(): 0.068,(28.1% identity in 185 aa overlap); P00778|PRLA_LYSEN|ALPHA-LP ALPHA-LYTIC PROTEASE PRECURSOR (397 aa), FASTA scores: opt: 154, E(): 0.074, (26.75% identity in 172 aa overlap); etc. Also similar with Q50618|YI15_MYCTU|Rv1815|MT1863|MTCY1A11.28c HYPOTHETICAL 22.8 KDA PROTEIN from Mycobacterium tuberculosis (221 aa),FASTA scores: opt: 134, E(): 0.69, (30.95% identity in 181 aa overlap).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS40471304047828-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3692c|Mb3692c
MQTAHRRFAAAFAAVLLAVVCLPANTAAADDKLPLGGGAGIVVNGDTMCTLTTIGHDKNGDLIGFTSAHCGGPGAQIAAEGAENAGPVGIMVAGNDGLDYAVIKFDPAKVTPVAVFNGFAINGIGPDPSFGQIACKQGRTTGNSCGVTWGPGESPGTLVMQVCGGPGDSGAPVTVDNLLVGMIHGAFSDNLPSCITKYIPLHTPAVVMSINADLADINAKNRPGAGFVPVPA
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