Gene Mb3704 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb3704
Gene length1023 bp
IdentifierMb3704
Location 4056123 bp
Protein summary information
Molecular mass35856.3 Da
Isoelectric point5.0862
Protein length340 amino acids
Orthologs
M. tuberculosis H37RvRv3679
M. tuberculosis MTBC0mtbc0_003899
Cross-references
UniProtKB/TrEMBLX2BPJ1, P65090
SWISS-MODELP65090
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE ANION TRANSPORTER ATPASE
CommentsMb3704, -, len: 340 aa. Equivalent to Rv3679, len: 340 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 340 aa overlap). Probable anion transporting ATPase (EC 3.6.1.-), equivalent to Q9CB88|ML2305 PROBABLE ANION TRANSPORTER PROTEIN from Mycobacterium leprae (341 aa), FASTA scores: opt: 1810,E(): 2.1e-98, (84.15% identity in 341 aa overlap). Also highly similar to Q9XA36|SCH17.11 PUTATIVE ION-TRANSPORTING ATPASE from Streptomyces coelicolor (325 aa), FASTA scores: opt: 989, E(): 1.4e-50, (52.15% identity in 328 aa overlap); and similar to many anion transporting ATPases (principally arsenite transporters) e.g. O50593|ARSA_ACIMU ARSENICAL PUMP-DRIVING ATPASE (ARSENITE-TRANSLOCATING ATPASE) from Acidiphilium multivorum (583 aa), FASTA scores: opt: 225, E(): 8.1e-06,(25.1% identity in 319 aa overlap); AAG43231|ARSA ARSENITE ACITVATED ATPASE from Salmonella typhimurium plasmid R46 FASTA scores: opt: 211, E(): 5.3e-05, (26.95% identity in 267 aa overlap); P52145|ARA2_ECOLI|ARSA ARSENICAL PUMP-DRIVING ATPASE from Escherichia coli plasmid IncN R46 (583 aa), FASTA scores: opt: 211, E(): 5.3e-05, (26.95% identity in 267 aa overlap); etc. Contains PS00017 ATP/GTP-binding site motif A (P-loop). SOME SIMILARITY TO THE ARSA ATPASE FAMILY.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS40561234057145+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3704|Mb3704
MVATTSSGGSSVGWPSRLSGVRLHLVTGKGGTGKSTIAAALALTLAAGGRKVLLVEVEGRQGIAQLFDVPPLPYQELKIATAERGGQVNALAIDIEAAFLEYLDMFYNLGIAGRAMRRIGAVEFATTIAPGLRDVLLTGKIKETVVRLDKNKLPVYDAIVVDAPPTGRIARFLDVTKAVSDLAKGGPVHAQSEGVVKLLHSNQTAIHLVTLLEALPVQETLEAIEELAQMELPIGSVIVNRNIPAHLEPQDLAKAAEGEVDADSVRAGLLTAGVKLPDADFAGLLTETIQHATRITARAEIAQQLDALQVPRLELPTVSDGVDLGSLYELSESLAQQGVR
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