Gene Mb3705 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb3705
Gene length1161 bp
IdentifierMb3705
Location 4057142 bp
Protein summary information
Molecular mass41404.6 Da
Isoelectric point5.864
Protein length386 amino acids
Orthologues
M. tuberculosisRv3680
Cross-references
InterProIPR016300, IPR025723, IPR027417
UniProtKB/TrEMBLQ7TVY5
SWISS-MODELA0A1R3Y4W6
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE ANION TRANSPORTER ATPASE
CommentsMb3705, -, len: 386 aa. Equivalent to Rv3680, len: 386 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 386 aa overlap). Probable anion transporting ATPase (EC 3.6.1.-), equivalent to Q9CB87|ML2306 PROBABLE ANION TRANSPORTER PROTEIN from Mycobacterium leprae (381 aa), FASTA scores: opt: 2131,E(): 6.5e-120, (88.1% identity in 370 aa overlap). Also highly similar, but shorter 29 aa, to Q9XA35|SCH17.12 PUTATIVE ION-TRANSPORTING ATPASE from Streptomyces coelicolor (481 aa), FASTA scores: opt: 1190, E(): 1.1e-63, (51.25% identity in 441 aa overlap); and similar to many anion transporting ATPases e.g. Q9UZA6|PAB1555 ANION TRANSPORTING ATPASE from Pyrococcus abyssi (330 aa) FASTA scores: opt: 242, E(): 3e-07, (24.6% identity in 297 aa overlap); Q9P7F8|SPAC1142.06 PUTATIVE ARSENITE-TRANSLOCATING from Schizosaccharomyces pombe (Fission yeast) (329 aa), FASTA scores: opt: 239, E(): 4.5e-07, (27.9% identity in 197 aa overlap); Q9HS79|ARSA1|VNG0365G ARSENICAL PUMP-DRIVING ATPASE from Halobacterium sp. strain NRC-1 (347 aa), FASTA scores: opt: 238, E(): 5.4e-07, (29.35% identity in 358 aa overlap); etc. Contains PS00017 ATP/GTP-binding site motif A (P-loop).
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS40571424058302+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3705|Mb3705
MSVTPKTLDMGAILADTSNRVVVCCGAGGVGKTTTAAALALRAAEYGRTVVVLTIDPAKRLAQALGINDLGNTPQRVPLAPEVPGELHAMMLDMRRTFDEMVMQYSGPERAQSILDNQFYQTVATSLAGTQEYMAMEKLGQLLSQDRWDLIVVDTPPSRNALDFLDAPKRLGSFMDSRLWRLLLAPGRGIGRLITGVMGLAMKALSTVLGSQMLADAAAFVQSLDATFGGFREKADRTYALLKRRGTQFVVVSAAEPDALREASFFVDRLSQESMPLAGLVFNRTHPMLCALPIERAIDAAETLDAETTDSDATSLAAAVLRIHAERGQTAKREIRLLSRFTGANPTVPVVGVPSLPFDVSDLEALRALADQLTTVGNDAGRAAGR
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