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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE ANION TRANSPORTER ATPASE
CommentsMb3705, -, len: 386 aa. Equivalent to Rv3680, len: 386 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 386 aa overlap). Probable anion transporting ATPase (EC 3.6.1.-), equivalent to Q9CB87|ML2306 PROBABLE ANION TRANSPORTER PROTEIN from Mycobacterium leprae (381 aa), FASTA scores: opt: 2131,E(): 6.5e-120, (88.1% identity in 370 aa overlap). Also highly similar, but shorter 29 aa, to Q9XA35|SCH17.12 PUTATIVE ION-TRANSPORTING ATPASE from Streptomyces coelicolor (481 aa), FASTA scores: opt: 1190, E(): 1.1e-63, (51.25% identity in 441 aa overlap); and similar to many anion transporting ATPases e.g. Q9UZA6|PAB1555 ANION TRANSPORTING ATPASE from Pyrococcus abyssi (330 aa) FASTA scores: opt: 242, E(): 3e-07, (24.6% identity in 297 aa overlap); Q9P7F8|SPAC1142.06 PUTATIVE ARSENITE-TRANSLOCATING from Schizosaccharomyces pombe (Fission yeast) (329 aa), FASTA scores: opt: 239, E(): 4.5e-07, (27.9% identity in 197 aa overlap); Q9HS79|ARSA1|VNG0365G ARSENICAL PUMP-DRIVING ATPASE from Halobacterium sp. strain NRC-1 (347 aa), FASTA scores: opt: 238, E(): 5.4e-07, (29.35% identity in 358 aa overlap); etc. Contains PS00017 ATP/GTP-binding site motif A (P-loop).
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS40571424058302+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3705|Mb3705
MSVTPKTLDMGAILADTSNRVVVCCGAGGVGKTTTAAALALRAAEYGRTVVVLTIDPAKRLAQALGINDLGNTPQRVPLAPEVPGELHAMMLDMRRTFDEMVMQYSGPERAQSILDNQFYQTVATSLAGTQEYMAMEKLGQLLSQDRWDLIVVDTPPSRNALDFLDAPKRLGSFMDSRLWRLLLAPGRGIGRLITGVMGLAMKALSTVLGSQMLADAAAFVQSLDATFGGFREKADRTYALLKRRGTQFVVVSAAEPDALREASFFVDRLSQESMPLAGLVFNRTHPMLCALPIERAIDAAETLDAETTDSDATSLAAAVLRIHAERGQTAKREIRLLSRFTGANPTVPVVGVPSLPFDVSDLEALRALADQLTTVGNDAGRAAGR
      
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