Gene Mb3709
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE LYASE |
| Comments | Mb3709, -, len: 346 aa. Equivalent to Rv3684, len: 346 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 346 aa overlap). Probable lyase (EC 4.-.-.-), and more specifically a cysteine synthase (EC 4.2.99.8), highly similar to many lyases e.g. Q9K3N2|SCG20A.08c PUTATIVE LYASE from Streptomyces coelicolor (374 aa), FASTA scores: opt: 1469, E(): 3.7e-85, (63.35% identity in 341 aa overlap) (shorter 31 aa at N-terminus); Q9KT44|VC1061 CYSTEINE SYNTHASE (EC 4.2.99.8)/CYSTATHIONINE BETA-SYNTHASE FAMILY PROTEIN from Vibrio cholerae (355 aa), FASTA scores: opt: 1366, E(): 1.1e-78, (63.25% identity in 321 aa overlap); Q9I4R3|PA1061 HYPOTHETICAL PROTEIN from Pseudomonas aeruginosa (365 aa), FASTA scores: opt: 1311, E(): 3.2e-75, (59.8% identity in 341 aa overlap); Q9PH18|XF0128 CYSTEINE SYNTHASE from Xylella fastidiosa (390 aa), FASTA scores: opt: 1288, E(): 9.5e-74, (58.55% identity in 333 aa overlap) (shorter 34 aa at N-terminus); P55708|Y4XP_RHISN PUTATIVE CYSTEINE SYNTHASE from Rhizobium sp. strain NGR234 plasmid sym pNGR234a (336 aa),FASTA scores: opt: 376, E(): 2.1e-16, (29.2% identity in 315 aa overlap); etc. Equivalent to AAK48153 from Mycobacterium tuberculosis strain CDC1551 (368 aa) but shorter 22 aa. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 4062786 | 4063826 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3709|Mb3709
MIEADARRSADTHLLRYPLPAAWCTDVDVELYLKDETTHITGSLKHRLARSLFLYALCNGWINENTTVVEASSGSTAVSEAYFAALLGLPFIAVMPAATSASKIALIESQGGRCHFVQNSSQVYAEAERVAKETGGHYLDQFTNAERATDWRGNNNIAESIYVQMREEKHPTPEWIVVGAGTGGTSATIGRYIRYRRHATRLCVVDPENSAFFPAYSEGRYDIVMPTSSRIEGIGRPRVEPSFLPGVVDRMVAVPDAASIAAARHVSAVLGRRVGPSTGTNLWGAFGLLAEMVKQGRSGSVVTLLADSGDRYADTYFSDEWVSAQGLDPAGPAAALVEFERSCRWT
Bibliography
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