Gene Mb3717 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemoxR2
Gene length1077 bp
IdentifierMb3717
Location 4070863 bp
Protein summary information
Molecular mass37936.4 Da
Isoelectric point5.4253
Protein length358 amino acids
Cross-references
InterProIPR011703, IPR016366, IPR027417
UniProtKB/TrEMBLQ7TVX3
SWISS-MODELA0A1R3Y6H5
General annotation
TypeCDS
FunctionUnknown
Productprobable methanol dehydrogenase transcriptional regulatory protein moxr2
CommentsMb3717, moxR2, len: 358 aa. Equivalent to Rv3692,len: 358 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 358 aa overlap). Probable moxR2,methanol dehydrogenase regulatory protein, highly similar (generally longer at N-terminus) to Q9KYW3|SCE33.20 PUTATIVE REGULATORY PROTEIN from Streptomyces coelicolor (329 aa), FASTA scores: opt: 1523, E(): 4.2e-74, (70.9% identity in 330 aa overlap); Q9Z538|SC9B2.21c PUTATIVE REGULATORY PROTEIN from Streptomyces coelicolor (332 aa) FASTA scores: opt: 1008, E(): 1.1e-46, (50.8% identity in 313 aa overlap); Q9UZ67|MOXR-3|PAB0848 METHANOL DEHYDROGENASE REGULATORY PROTEIN from Pyrococcus abyssi (314 aa), FASTA scores: opt: 989, E(): 1.1e-45, (50.65% identity in 302 aa overlap); Q9AAN1|CC0566 MOXR PROTEIN from Caulobacter crescentus (323 aa), FASTA scores: opt: 988, E(): 1.3e-45, (52.3% identity in 306 aa overlap); etc. Also similar to O53170|MTV007.26|MOXR|Rv1479 from Mycobacterium tuberculosis (377 aa); and O07392|AF002133_6|MOXR from Mycobacterium avium (309 aa). Also high similarity with several hypothetical bacterial proteins.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS40708634071939+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3717|moxR2
MTQSASNPQAPPTQTPGAELPGYPPQAGGAPTAAPSGPHPHRAEAESARDALLALRAEVAKAVVGQDGVISGLVIALLCRGHVLLEGVPGVAKTLIVRAMSAALQLEFKRVQFTPDLMPGDVTGSLVYDARTAEFVFRPGPVFTNLLLADEINRTPPKTQAALLEAMEERQVSVEGEPKPLPNPFIVAATQNPIEYEGTYQLPEAQLDRFLLKLNVTLPARDSEIAILDRHAHGFDPRDLSAINPVAGPAELAAGREAVRHVLVANEVLGYIVDIVGATRSSPALQLGVSPRGATALLGTARSWAWLSGRDYVTPDDVKAMARPTLRHRVMLRPEAELEGATPDGVLDGILASVPVPR
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