Gene Mb3761c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nametgs2
Gene length1365 bp
IdentifierMb3761c
Location 4121986 bp
Protein summary information
Molecular mass49303.8 Da
Isoelectric point6.8451
Protein length454 amino acids
Orthologs
M. tuberculosis H37RvRv3734c
M. tuberculosis MTBC0mtbc0_003959
Cross-references
UniProtKB/TrEMBLX2BPF5, P67211
SWISS-MODELP67211
General annotation
TypeCDS
FunctionUnknown
Productputative triacylglycerol synthase (diacylglycerol acyltransferase) tgs2
CommentsMb3761c, -, len: 454 aa. Equivalent to Rv3734c,len: 454 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 454 aa overlap). Hypothetical protein,highly similar to O69707|Y1E0_MYCTU|Rv3740c|MT3848|MTV025.088c HYPOTHETICAL PROTEIN from Mycobacterium tuberculosis (448 aa), FASTA scores: opt: 1917, E(): 1.3e-111, (61.4% identity in 451 aa overlap); and similar to many other proteins from Mycobacterium tuberculosis (strains H37Rv and CDC1551) e.g. P71694|YE43_MYCTU|Rv1425|MT1468|MTCY21B4.43|MTCY493.29c (459 aa), FASTA scores: opt: 824, E(): 1.1e-43, (36.5% identity in 460 aa overlap); Q50680|YM85_MYCTU|Rv2285|MT2343|MTCY339.25c (445 aa) FASTA scores: opt: 766, E(): 4.1e-40, (36.4% identity in 453 aa overlap); etc. Also similar to Q9RIU8|SCM11.13c HYPOTHETICAL 47.1 KDA PROTEIN from Streptomyces coelicolor (446 aa), FASTA scores: opt: 331, E(): 4.3e-13, (32.9% identity in 468 aa overlap); and Q9X7A8|ML1244|MLCB1610.05 CONSERVED MEMBRANE PROTEIN from Mycobacterium leprae (491 aa), FASTA scores: opt: 296, E(): 7e-11, (28.35% identity in 413 aa overlap). Contains PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. Start site chosen by homology, but may extend further upstream.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS41219864123350-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3761c|tgs2
MDLMMPNDSMFLFIESREHPMHVGGLSLFEPPQGAGPEFVREFTERLVANDEFQPMFRKHPATIGGGIARVAWAYDDDIDIDYHVRRSALPSPGRVRDLLELTSRLHTSLLDRHRPLWELHVVEGLNDGRFAMYTKMHHALIDGVSAMKLAQRTLSADPDDAEVRAIWNLPPRPRTRPPSDGSSLLDALFKMAGSVVGLAPSTLKLARAALLEQQLTLPFAAPHSMFNVKVGGARRCAAQSWSLDRIKSVKQAAGVTVNDAVLAMCAGALRYYLIERNALPDRPLIAMVPVSLRSKEDADAGGNLVGSVLCNLATHVDDPAQRIQTISASMDGNKKVLSELPQLQVLALSALNMAPLTLAGVPGFLSAVPPPFNIVISNVPGPVDPLYYGTARLDGSYPLSNIPDGQALNITLVNNAGNLDFGLVGCRRSVPHLQRLLAHLESSLKDLEQAVGI
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