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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CONSERVED TRANSMEMBRANE PROTEIN
CommentsMb3764, -, len: 529 aa. Equivalent to Rv3737, len: 529 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 529 aa overlap). Probable conserved transmembrane protein, similar to others and also some hypothetical proteins e.g. AAK61331|THRE THREONINE EXPORT CARRIER from Corynebacterium glutamicum (Brevibacterium flavum) (489 aa), FASTA scores: opt: 773, E(): 1.8e-36,(37.25% identity in 424 aa overlap); Q9X8J0|SCE9.17 PUTATIVE MEMBRANE PROTEIN from Streptomyces coelicolor (578 aa), FASTA scores: opt: 642, E(): 5.4e-29, (31.6% identity in 481 aa overlap) (shorter 119 aa at N-terminus); Q9CJU6|PM1895 HYPOTHETICAL PROTEIN from Pasteurella multocida (262 aa), FASTA scores: opt: 233,E(): 4.1e-06, (25.0% identity in 256 aa overlap); Q9S267|SCI30A.06 PUTATIVE INTEGRAL MEMBRANE PROTEIN from Streptomyces coelicolor (297 aa), FASTA scores: opt: 163,E(): 0.042, (29.65% identity in 263 aa overlap); etc. Also partially similar to O05435|Rv3910|MTCY15F10.01c|MTV028.01 HYPOTHETICAL 123.6 KDA PROTEIN from Mycobacterium tuberculosis (1184 aa) (34.4% identity in 125 aa overlap).
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS41251594126748+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3764|Mb3764
MDQDRSDNTALRRGLRIALRGRRDPLPVAGRRSRTSGGIGDLHTRKVLDLTIRLAEVMLSSGSGTADVVATAQDVAQAYQLTDCVVDITVTTIIVSALATTDTPPVTIMRSVRTRSTDYSRLAELDRLVQRITSGGVAVDQAHEAMDELTERPHPYPRWLATAGAAGFALGVAMLLGGTWLTCVLAAVTSGVIDRLGRLLNRIGTPLFFQRVFGAGIATLVAVAAYLIAGQDPTALVATGIVVLLSGMTLVGSMQDAVTGYMLTALARLGDALFLTAGIVVGILISLRGVTNAGIQIELHVDATTTLATPGMPLPILVAVSGAALSGVCLTIASYAPLRSVATAGLSAGLAELVLIGLGAAGFGRVVATWTAAIGVGFLATLISIRRQAPALVTATAGIMPMLPGLAVFRAVFAFAVNDTPDGGLTQLLEAAATALALGSGVVLGEFLASPLRYGAGRIGDLFRIEGPPGLRRAVGRVVRLQPAKSQQPTGTGGQRWRSVALEPTTADDVDAGYRGDWPATCTSATEVR
      
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