Gene Mb3778c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb3778c
Gene length459 bp
IdentifierMb3778c
Location 4135541 bp
Protein summary information
Molecular mass15877.3 Da
Isoelectric point6.5169
Protein length152 amino acids
Orthologs
M. tuberculosis MTBC0mtbc0_003976
M. tuberculosis H37RvRv3752c
Cross-references
InterProIPR002125, IPR016192, IPR016193, IPR028883
UniProtKB/TrEMBLQ7TVS1
SWISS-MODELA0A1R3Y550
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE CYTIDINE/DEOXYCYTIDYLATE DEAMINASE
CommentsMb3778c, -, len: 152 aa. Equivalent to Rv3752c,len: 152 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 152 aa overlap). Probable cytidine/deoxycytidylate deaminase (EC 3.5.4.-),equivalent to Q9CB32|ML2474 POSSIBLE CYTIDINE/DEOXYCYTIDYLATE DEAMINASE from Mycobacterium leprae (171 aa), FASTA scores: opt: 890, E(): 1.6e-50,(88.1% identity in 151 aa overlap). Also highly similar to other deaminases and hypothetical proteins e.g. Q9AK79|2SCD60.04c PUTATIVE DEAMINASE from Streptomyces coelicolor (143 aa), FASTA scores: opt: 559, E(): 2.9e-29,(66.45% identity in 146 aa overlap); Q9F9W7 CYTOSINE DEAMINASE from Bifidobacterium longum (143 aa) FASTA scores: opt: 512, E(): 3.1e-26, (54.85% identity in 144 aa overlap); P21335|YAAJ_BACSU HYPOTHETICAL 17.8 KDA PROTEIN from Bacillus subtilis (161 aa), FASTA scores: opt: 425,E(): 1.4e-20, (47.7% identity in 151 aa overlap); AAK74212|SP0020 CYTIDINE/DEOXYCYTIDYLATE DEAMINASE FAMILY PROTEIN from Streptococcus pneumoniae (155 aa), FASTA scores: opt: 401, E(): 4.7e-19, (46.25% identity in 147 aa overlap); P30134|YFHC_ECOLI|B2559 HYPOTHETICAL 20.0 KDA PROTEIN from Escherichia coli strain K12 (178 aa), FASTA scores: opt: 397, E(): 9.5e-19, (47.0% identity in 149 aa overlap); etc. Contains PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. BELONGS TO THE CYTIDINE AND DEOXYCYTIDYLATE DEAMINASES FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS41355414135999-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3778c|Mb3778c
MTTDEDLIRAALAVAATAGPRDVPVGAVVVGADGTELARAVNAREALGDPTAHAEILAMRLAAGVLGDGWRLEGTTLAVTVEPCTMCAGALVLARVARLVFGAWEPKTGAVGSLWDVVRDRRLNHRPEVRGGVLARECAAPLEAFFARQRLG
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