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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productpossible hydrolase
CommentsMb3788c, -, len: 626 aa. Equivalent to Rv3762c,len: 626 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 626 aa overlap). Possible hydrolase (EC 3.-.-.-), highly similar to hypothetical proteins and beta-lactamases (EC 3.5.2.6) e.g. Q9RL04|SC5G9.23 HYPOTHETICAL 70.3 KDA PROTEIN from Streptomyces coelicolor (648 aa), FASTA scores: opt: 2088, E(): 3.7e-124, (52.9% identity in 624 aa overlap); P32717|YJCS_ECOLI|B4083 HYPOTHETICAL 73.2 KDA PROTEIN from Escherichia coli strain K12 (661 aa), FASTA scores: opt: 1911, E(): 5.7e-113,(46.9% identity in 631 aa overlap); Q9A824|CC1540 METALLO-BETA-LACTAMASE FAMILY PROTEIN from Caulobacter crescentus (647 aa), FASTA scores: opt: 1891, E(): 1e-111,(48.55% identity in 628 aa overlap); Q08347|YOL164W CHROMOSOME XV READING FRAME ORF from Saccharomyces cerevisiae (Baker's yeast) (646 aa) FASTA scores: opt: 1829, E(): 8.4e-108, (45.7% identity in 615 aa overlap); Q9I5I9|PA0740 PROBABLE BETA-LACTAMASE from Pseudomonas aeruginosa (658 aa), FASTA scores: opt: 1699, E(): 1.4e-99, (43.15% identity in 630 aa overlap); Q52556|SDSA ALKYL SULFATASE (protein involved in the degradation of sulfate esters of long-chain primaryal cohols e.g. SDS sodium dodecyl sulfate) from Pseudomonas sp (528 aa),FASTA scores: opt: 841, E(): 1.7e-45, (33.7% identity in 534 aa overlap); etc. N-terminual end also highly similar to Q48790|SEPA SEPA PROTEIN (protein implicated in cell separation) from Listeria monocytogenes (391 aa), FASTA scores: opt: 1256, E(): 8.3e-72, (49.6% identity in 363 aa overlap). Also slight similarity to P96253|Rv0407|MTCY22G10.03 HYPOTHETICAL 37.0 KDA PROTEIN from Mycobacterium tuberculosis (336 aa).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS41432904145170-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3788c|Mb3788c
MPMEHKPPTAVIQAAHGEHSLPLHDTTDFDDADRGFIAALSPCVIKAADGRVVWDNDAYSFLDGAAPTSVHPSLWRQSQLTAKQGLYQVVPGIYQVRGFDISNISFVEGDTGLIVIDPLVSTEVAAAALDLYRAHRGADRPVVAVIYTHSHVDHFGGVLGGTTQADVDAGKVAVLAPEGFTAHAVQENIYAGSAMMRRAGYMYGTVLARGLRGHVGCGLGQTLSTGEVSLVVPTVDITETGETHTIDGVEIEFQMAPGTEAPAEMHFYFPRFRALCMAENATHNLHNLLTLRGALVRDPRAWSGYLTEAIDTFADRTDVVFASHHWPTWGREKIVEFLSQQRDMHSYLHDQTLRLLNQGYTGVEIAEMFQLPPALQRAWHTHGYYGSVSHNVKAIYQRYMGWFDGNPGWLWPHPPEALAPRYVDALGGIDRVLELAREAFDAGDFRWAATLLDHAVFADSEHAAARGLYADTLEQLAYGAECATWRNFFLTGAAELRDGNPGSSGQVPAPTFFAQLTPDQIFDVLAISINGPRAWDLDLAIDFTFTEPDVNYRLTLRNGVLIHRKLPADPATANATVTVGDKVRLVAAALGDISSPGFEVFGDRTVLQTFLSVLDRPDSAFNIVTP
      
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