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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE O-ANTIGEN/LIPOPOLYSACCHARIDE TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER RFBE
CommentsMb3810, rbfE, len: 273 aa. Equivalent to Rv3781,len: 273 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 273 aa overlap). Probable rfbE,polysaccharide-transport ATP-binding protein ABC transporter (see citation below), involved in O-antigen/lipopolysaccharides (LPS) transport, equivalent to Q9CDA0|ML0114 PUTATIVE ABC TRANSPORTER ATP-BINDING COMPONENT from Mycobacterium leprae (272 aa), FASTA scores: opt: 1581, E(): 3e-83, (91.4% identity in 267 aa overlap). Also highly similar to AAK71283 LPS/O-ANTIGEN EXPORT PERMEASE from Coxiella burnetii (258 aa), FASTA scores: opt: 793, E(): 2.5e-38, (45.45% identity in 253 aa overlap); Q9PAF0|XF2568 ABC TRANSPORTER ATP-BINDING PROTEIN from Xylella fastidiosa (246 aa), FASTA scores: opt: 758, E(): 2.4e-36, (47.75% identity in 243 aa overlap); Q56903|RFBE_YEREN O-ANTIGEN EXPORT SYSTEM ATP-BINDING PROTEIN from Yersinia enterocolitica (239 aa),FASTA scores: opt: 697, E(): 7e-33, (48.65% identity in 224 aa overlap); Q50863|RFBB_MYXXA O-ANTIGEN EXPORT SYSTEM ATP-BINDING from Myxococcus xanthus (437 aa), FASTA scores: opt: 605, E(): 2e-27, (42.05% identity in 207 aa overlap); etc. Contains PS00017 ATP/GTP-binding site motif A (P-loop). BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY (ABC TRANSPORTERS).
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS41638244164645+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3810|rfbE
MSDPHHPHIQTHNAWVEFPIFDAKSRSLKKAVLGKAGGTIGRNNSNVVVIEALRDITMELNLGDRVGLVGHNGAGKSTLLRLLSGIYEPTRGWAKVTGRVAPVFDLGIGMDPEISGYENIIIRGLFLGQTRKQMQAKVDEIAEFTELGEYLSMPLRTYSTGMRVRLAMGVVTSIDPEILLLDEGIGAVDADFLRKAQSRLQNLVERSGILVFASHSNEFLARLCKTAIWIDHGVIRLAGGIEEVVRAYEGEDAARHVREVLAETQADRQNVQG
      
Bibliography
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