Gene Mb3831c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefadD32
Gene length1914 bp
IdentifierMb3831c
Location 4197426 bp
Protein summary information
Molecular mass69260.1 Da
Isoelectric point6.1033
Protein length637 amino acids
Orthologs
M. tuberculosis MTBC0mtbc0_004029
M. tuberculosis H37RvRv3801c
Cross-references
UniProtKB/TrEMBLX2BPL9, Q7TTR2
General annotation
TypeCDS
FunctionUnknown
Productfatty-acid-amp ligase fadd32 (fatty-acid-amp synthetase) (fatty-acid-amp synthase). also shown to have acyl-acp ligase activity.
CommentsMb3831c, fadD32, len: 637 aa. Equivalent to Rv3801c, len: 637 aa, from Mycobacterium tuberculosis strain H37Rv, (99.8% identity in 637 aa overlap). Probable fadD32, fatty-acid-CoA synthetase (EC 6.2.1.-), equivalent to Q9CDB2|FADD32|ML0100 PUTATIVE ACYL-COA SYNTHETASE from Mycobacterium leprae (635 aa), FASTA scores: opt: 3892,E(): 0, (93.05% identity in 632 aa overlap); and highly similar to others from Mycobacterium leprae. Also similar to others from Mycobacterium tuberculosis e.g. P95288|FADD31|Rv1925|MTCY09F9.39c (620 aa), FASTA scores: opt: 1567, E(): 1.7e-88, (47.05% identity in 612 aa overlap); MTCY338_18, MTCY349_40, MTV005_21, MTCY24G1_8,MTCY19G5_7, MTCY4D9_17; and MBU75685_1 ACYL-COA LIGASE from Mycobacterium bovis.
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS41974264199339-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3831c|fadD32
MFVTGESGMAYHNPFIVNGKIRFPANTNLVRHVEKWAKVRGDKLAYRFLDFSTERDGVARDILWSDFSARNRAVGARLQQVTQPGDRVAILCPQNLDYLISFFGALYSGRIAVPLFDPAEPGHVGRLHAVLDDCAPSTILTTTDSAEGVRKFIRARSAKERPRVIAVDAVPTEVAATWQQPEANEETVAYLQYTSGSTRIPSGVQITHLNLPTNVVQVLNALEGQEGDRGVSWLPFFHDMGLITVLLASVLGHSFTFMTPAAFVRRPGRWIRELARKPGETGGTFSAAPNFAFEHAAVRGVPRDDEPPLDLSNVKGILNGSEPVSPASMRKFFEAFAPYGLKQTAVKPSYGLAEATLFVSTTPMDEVPTVIHVDRDELNNQRFVEVAADAPNAVAQVSAGKVGVSEWAVIVDADTASELPDGQIGEIWLHGNNLGTGYWGKEEESAQTFKNILKSRISESRAEGAPDDALWVRTGDYGTYFKDHLYIAGRIKDLVIIDGRNHYPQDLECTAQESTKALRVGYVAAFSVPANQLPQTVFDDSHAGLKFDPEDTSEQLVIVGERAAGTHKLDHQPIVDDIRAAIAVGHGVTVRDVLLVSAGTIPRTSSGKIGRRACRAAYLDGSLRSGVGSPTVFATSD
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