Gene Mb3831c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | fatty-acid-amp ligase fadd32 (fatty-acid-amp synthetase) (fatty-acid-amp synthase). also shown to have acyl-acp ligase activity. |
| Comments | Mb3831c, fadD32, len: 637 aa. Equivalent to Rv3801c, len: 637 aa, from Mycobacterium tuberculosis strain H37Rv, (99.8% identity in 637 aa overlap). Probable fadD32, fatty-acid-CoA synthetase (EC 6.2.1.-), equivalent to Q9CDB2|FADD32|ML0100 PUTATIVE ACYL-COA SYNTHETASE from Mycobacterium leprae (635 aa), FASTA scores: opt: 3892,E(): 0, (93.05% identity in 632 aa overlap); and highly similar to others from Mycobacterium leprae. Also similar to others from Mycobacterium tuberculosis e.g. P95288|FADD31|Rv1925|MTCY09F9.39c (620 aa), FASTA scores: opt: 1567, E(): 1.7e-88, (47.05% identity in 612 aa overlap); MTCY338_18, MTCY349_40, MTV005_21, MTCY24G1_8,MTCY19G5_7, MTCY4D9_17; and MBU75685_1 ACYL-COA LIGASE from Mycobacterium bovis. |
| Functional category | Lipid metabolism |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 4197426 | 4199339 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3831c|fadD32
MFVTGESGMAYHNPFIVNGKIRFPANTNLVRHVEKWAKVRGDKLAYRFLDFSTERDGVARDILWSDFSARNRAVGARLQQVTQPGDRVAILCPQNLDYLISFFGALYSGRIAVPLFDPAEPGHVGRLHAVLDDCAPSTILTTTDSAEGVRKFIRARSAKERPRVIAVDAVPTEVAATWQQPEANEETVAYLQYTSGSTRIPSGVQITHLNLPTNVVQVLNALEGQEGDRGVSWLPFFHDMGLITVLLASVLGHSFTFMTPAAFVRRPGRWIRELARKPGETGGTFSAAPNFAFEHAAVRGVPRDDEPPLDLSNVKGILNGSEPVSPASMRKFFEAFAPYGLKQTAVKPSYGLAEATLFVSTTPMDEVPTVIHVDRDELNNQRFVEVAADAPNAVAQVSAGKVGVSEWAVIVDADTASELPDGQIGEIWLHGNNLGTGYWGKEEESAQTFKNILKSRISESRAEGAPDDALWVRTGDYGTYFKDHLYIAGRIKDLVIIDGRNHYPQDLECTAQESTKALRVGYVAAFSVPANQLPQTVFDDSHAGLKFDPEDTSEQLVIVGERAAGTHKLDHQPIVDDIRAAIAVGHGVTVRDVLLVSAGTIPRTSSGKIGRRACRAAYLDGSLRSGVGSPTVFATSD
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