Gene Mb3850c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | POSSIBLE CONSERVED POLYKETIDE SYNTHASE ASSOCIATED PROTEIN PAPA2 |
| Comments | Mb3850c, papA2, len: 468 aa. Equivalent to Rv3820c,len: 468 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 468 aa overlap). Possible papA2,conserved polyketide synthase (PKS) associated protein,highly similar to Q49618|PAPA3|ML1230|B1170_C1_180 PKS-ASSOCIATED PROTEIN A3 from Mycobacterium leprae (471 aa), FASTA scores: opt: 1660, E(): 2.7e-102, (53.95% identity in 456 aa overlap). Also similar to Q9F2R3|SCD65.19c HYPOTHETICAL 52.8 KDA PROTEIN from Streptomyces coelicolor (473 aa), FASTA scores: opt: 575,E(): 1.8e-30, (27.8% identity in 464 aa overlap); and weakly similar to part of other proteins. Also high similarity with other PKS-ASSOCIATED PROTEINS from Mycobacterium tuberculosis; O50438|PAPA3|Rv1182|MTV005.18 (472 aa), FASTA scores: opt: 1694, E(): 1.5e-104, (53.8% identity in 461 aa overlap); and O07799|PAPA1|Rv3824c|MTCY409.06 (511 aa), FASTA scores: opt: 1664, E(): 1.6e-102, (53.9% identity in 462 aa overlap); and similar to C-terminal end of O53902|PAPA4|Rv1528c|MTV045.02 (165 aa), FASTA scores: opt: 186, E(): 4.1e-05, (37.9% identity in 66 aa overlap). |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 4220692 | 4222098 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3850c|papA2
MFSITTLRDWTPDPGSIICWHASPTAKAKARQAPISEVPPSYQQAQHLRRYRDHVARGLDMSRLMIFTWDLPGRCNIRAMNYAINAHLRRHDTYHSWFEFDNAEHIVRHTIADPADIEVVQAEHQNMTSAELRHHIATPQPLQWDCFLFGIIQSDDHFTFYASIAHLCVDPMIVGVLFIEIHMMYSALVGGDPPIELPPAGRYDDHCVRQYADTAALTLDSARVRRWVEFAANNDGTLPHFPLPLGDLSVPHTGKLLTETLMDEQQGERFEAACVAAGARFSGGVFACAALAERELTNCETFDVVTTTDTRRTPTELRTTGWFTGLVPITVPVASGLFDSAARVAQISFDSGKDLATVPFDRVLELARPETGLRPPRPGNFVMSFLDASIAPLSTVANSDLNFRIYDEGRVSHQVSMWVNRYQHQTTVTVLFPDNPIASESVANYIAAMKSIYIRTADGTLAILKPGT
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