Go to browser
virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductTRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY)
CommentsMb3860c, -, len: 209 aa. Equivalent to Rv3830c,len: 209 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 209 aa overlap). Probable transcriptional regulator tetR family, similar to others e.g. P39885|TCMR_STRGA TETRACENOMYCIN C TRANSCRIPTIONAL REPRESSOR from Streptomyces glaucescens (226 aa) FASTA scores: opt: 255, E(): 6.1e-10, (33.65% identity in 202 aa overlap); Q9RDR0|SC4A7.02 PUTATIVE TRANSCRIPTIONAL REGULATOR from Streptomyces coelicolor (227 aa) FASTA scores: opt: 230, E(): 2.8e-08, (30.05% identity in 213 aa overlap); Q9EWU3|3SC5B7.06 PUTATIVE REGULATORY PROTEIN from Streptomyces coelicolor (244 aa), FASTA scores: opt: 221, E(): 1.2e-07, (32.05% identity in 181 aa overlap); Q9AJ68|BUTR PUTATIVE TRANSCRIPTIONAL REPRESSOR from Streptomyces cinnamonensis (268 aa), FASTA scores: opt: 216, E(): 2.7e-07, (37.8% identity in 119 aa overlap); etc. Contains possible helix-turn-helix motif from aa 33-54, Score 1699 (+4.97 SD). SEEMS TO BELONG TO THE TETR/ACRR FAMILY OF TRANSCRIPTIONAL REGULATORS.
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS42413294241958-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3860c|Mb3860c
MVRPPQTARSERTREALRQAALVRFLAQGVEATSAEQIAEDAGVSLRTFYRHFRSKHDLLFADYDAGLHWFRAALDARPADESIIDSVQAAIFSFPYDVDAVTKIASLRRGELEPSRIVRHMREVEADFADAIQAQLRRRNCDIAGAPDARLHIAVTARCVAAAVFGAMEAWMLGSDRSLGELARVCHVALESLRVGISDTWTTLTVSS
      
Bibliography
No article yet recorded