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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductSERYL-TRNA SYNTHETASE SERS (SERINE--TRNA LIGASE) (SERRS) (SERINE TRANSLASE)
CommentsMb3864c, serS, len: 419 aa. Equivalent to Rv3834c,len: 419 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 419 aa overlap). Probable serS,seryl-tRNA synthetase (EC 6.1.1.11), equivalent to Q9CDC1|SERS|ML0082 PUTATIVE SERYL-TRNA SYNTHASE from Mycobacterium leprae (417 aa), FASTA scores: opt: 2361,E(): 8.5e-138, (85.8% identity in 416 aa overlap). Also highly similar many e.g. Q9ZBX1|SYS_STRCO|SERS|SCD78.28c from Streptomyces coelicolor (425 aa), FASTA scores: opt: 1594, E(): 1.2e-90, (59.75% identity in 425 aa overlap); Q9X199|SYS_THEMA|SERS|TM1379 from Thermotoga maritima (425 aa), FASTA scores: opt: 1083, E(): 3.3e-59, (43.3% identity in 425 aa overlap); P37464|SYS_BACSU|SERS from Bacillus subtilis (425 aa), FASTA scores: opt: 1015, E(): 5e-55, (39.3% identity in 425 aa overlap); etc. Contains PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. BELONGS TO CLASS-II AMINOACYL-TRNA SYNTHETASE FAMILY.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS42439284245187-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3864c|serS
MIDLKLLRENPDAVRRSQLSRGEDPALVDALLTADAARRAVISTADSLRAEQKAASKSVGGASPEERPPLLRRAKELAEQVKAAEADEVEAEAAFTAAHLAISNVIVDGVPAGGEDDYAVLDVVGEPSYLENPKDHLELGESLGLIDMQRGAKVSGSRFYFLTGRGALLQLGLLQLALKLAVDNGFVPTIPPVLVRPEVMVGTGFLGAHAEEVYRVEGDGLYLVGTSEVPLAGYHSGEILDLSRGPLRYAGWSSCFRREAGSHGKDTRGIIRVHQFDKVEGFVYCTPADAEHEHERLLGWQRQMLARIEVPYRVIDVAAGDLGSSAARKFDCEAWIPTQGAYRELTSTSNCTTFQARRLATRYRDASGKPQIAATLNGTLATTRWLVAILENHQRPDGSVRVPDALVPFVGVEVLEPVA
      
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