Gene Mb3867c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb3867c
Gene length699 bp
IdentifierMb3867c
Location 4247283 bp
Protein summary information
Molecular mass25019.1 Da
Isoelectric point4.8213
Protein length232 amino acids
Orthologs
M. tuberculosis MTBC0mtbc0_004067
M. tuberculosis H37RvRv3837c
Cross-references
InterProIPR013078
UniProtKB/TrEMBLQ7TVJ7
SWISS-MODELA0A1R3Y5N0
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE) (PHOSPHOGLYCERATE PHOSPHOMUTASE)
CommentsMb3867c, -, len: 232 aa. Equivalent to Rv3837c,len: 232 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 232 aa overlap). Probable phosphoglycerate mutase (EC 5.4.2.-), equivalent to Q9CDC3|ML0079 PUTATIVE PHOSPHOGLYCERATE MUTASE from Mycobacterium leprae (231 aa), FASTA scores: opt: 1116,E(): 7.3e-66, (71.55% identity in 232 aa overlap). Also similar to others e.g. Q9ZAX0|PGM 2,3-PDG DEPENDENT PHOSPHOGLYCERATE MUTASE from Amycolatopsis methanolica (205 aa), FASTA scores: opt: 474, E(): 6.4e-24, (41.85% identity in 203 aa overlap); Q9F3Q7|SC10F4.03 PUTATIVE ISOMERASE from Streptomyces coelicolor (224 aa) FASTA scores: opt: 349, E(): 1e-15, (33.2% identity in 223 aa overlap); Q9RDL0|SCC123.14c PUTATIVE PHOSPHOGLYCERATE MUTASE from Streptomyces coelicolor (223 aa), FASTA scores: opt: 256, E(): 1.2e-09, (34.0% identity in 203 aa overlap); Q9RVD2|DR1097 PUTATIVE PHOSPHOGLYCERATE MUTASE from Deinococcus radiodurans (232 aa), FASTA scores: opt: 201, E(): 5.1e-06, (31.45% identity in 175 aa overlap); etc. Also similar to P71724|Rv2419c|MTCY428.28|MTCY253.01 HYPOTHETICAL 24.2 KDA PROTEIN from Mycobacterium tuberculosis (223 aa), FASTA scores: opt: 210, E(): 1.3e-06, (32.0% identity in 172 aa overlap). Contains PS00175 Phosphoglycerate mutase family phosphohistidine signature.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS42472834247981-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3867c|Mb3867c
MSGRLVLLRHGQSYGNVERRLDTLPPGTALTPLGRDQARAFARSGCRRPALLAHSVAIRAYQTAAVVAAELDMVAHEVAGIHEVQVGELENRNDDEAVAEFNATYSRWHRGELDVPLPGGETANDVLDRYLPVLADLRMRYLDDGDWDGDIVVVSHSAAIRLAAAVLAGVDGNFVLDNHLENVESVVLAPITDGRWSCVQWGLRKPPFCPDPAEAAASPVTHAVTSSTDPMG
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