Gene Mb3919c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameesxC
Gene length375 bp
IdentifierMb3919c
Location 4307597 bp
Protein summary information
Molecular mass13511.3 Da
Isoelectric point10.4241
Protein length124 amino acids
Orthologs
M. tuberculosis H37RvRv3890c
Cross-references
InterProIPR010310, IPR020167
UniProtKB/TrEMBLQ7TVF1
SWISS-MODELA0A1R3Y5L3
General annotation
TypeCDS
FunctionUnknown
Productesat-6 like protein esxc (esat-6 like protein 11)
CommentsMb3919c, esxC, len: 124 aa. Similar to Rv3890c,len: 95 aa, from Mycobacterium tuberculosis strain H37Rv,(100% identity in 55 aa overlap). esxC, putative ESAT-6 like protein 11, equivalent to Q9K548|ES6B_MYCPA PUTATIVE ESAT-6 LIKE PROTEIN 11 (ORF3890C) from Mycobacterium paratuberculo sis (95 aa), FASTA scores: opt: 490, E(): 3.3e-26, (76.85% identity in 95 aa overlap). BELONGS TO THE ESAT6 FAMILY. REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a frameshift due to a single base deletion (c-*) leads to a longer product with a different COOH part compared to its homolog in Mycobacterium tuberculosis strain H37Rv (125 aa versus 95 aa).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS43075974307971-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3919c|esxC
MSDQITYNPGAVSDFASDVGSRAGQLHMIYEDTASKTNALQEFFAGHGAQGFFDARRRCCRGCRGSLRRWVSMGLPPATCWTTRSEPTRPSRACSKAGRGPSEGGVHARTARLPHLLLAASWLR
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