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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CONSERVED TRANSMEMBRANE PROTEIN
CommentsMb3952c, -, len: 366 aa. Equivalent to Rv3921c,len: 366 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 366 aa overlap). Probable conserved transmembrane protein, equivalent to Q9L7M1 HYPOTHETICAL 39.2 KDA PROTEIN from Mycobacterium paratuberculosis (353 aa), FASTA scores: opt: 2001, E(): 8.4e-100, (83.05% identity in 366 aa overlap); Q9CCX6|ML2710 PUTATIVE CONSERVED MEMBRANE PROTEIN from Mycobacterium leprae (380 aa), FASTA scores: opt: 1929, E(): 6.2e-96, (77.1% identity in 380 aa overlap); Q50205 CDS 27 on L222 from Mycobacterium leprae (312 aa) FASTA scores: opt: 1770,E(): 1.6e-87, (88.2% identity in 288 aa overlap). Also similar to other e.g. O54569|STH24.05 INNER MEMBRANE PROTEIN. from Streptomyces coelicolor (431 aa), FASTA scores: opt: 412, E(): 6.5e-15, (33.45% identity in 266 aa overlap); O84253|CT251 60 KDA INNER MEMBRANE PROTEIN from Chlamydia trachomatis (787 aa), FASTA scores: opt: 304,E(): 6e-09, (27.9% identity in 269 aa overlap); P29431|60IM_BUCAP 60 KDA INNER-MEMBRANE PROTEIN HOMOLOG from Buchnera aphidicola (subsp. Schizaphis graminum) (536 aa), FASTA scores: opt: 282, E(): 6.7e-08, (36.1% identity in 108 aa overlap); etc.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS43429294344029-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3952c|Mb3952c
MSLLFDFFSLDFIYYPVSWIMWVWYRLFAFVLGPSNFFAWALSVMFLVFTLRALLYKPFVRQIRTTRQMQELQPQIKALQKKYGKDRQRMALEMQKLQREHGFNPILGCLPMLAQIPVFLGLYHVLRSFNRTTGGFGQPHLSVIENRLTGNYVFSPVDVGHFLDANLFGAPIGAYMTQRSGLDAFVDFSRPALIAVGVPVMILAGIATYFNSRASIARQSAEAAANPQTAMMNKLALYVFPLGVVVGGPFLPLAIILYWFSNNIWTFGQQHYVFGMIEKEEEAKKQEAVRRRAANAPAPGAKPKRSPKTAPATNAAAPTEAGDTDDGAESDASTERPADTSNPARRNSGPSARTPRPGVRPKKRKR
      
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