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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionFunction unknown
ProductPPE family protein PPE29
CommentsRv1801, (MTV049.23), len: 423 aa. PPE29, Member of the Mycobacterium tuberculosis PPE family of glycine-rich proteins, most similar to AL022021|MTV049.29|Rv1808 (409 aa), FASTA scores: opt: 1229, E(): 0, (55.2% identity in 422 aa overlap).
Functional categoryPe/ppe
TranscriptomicsmRNA identified by microarray analysis and up-regulated after 96h of starvation (see citation below).
MutantNon-essential gene for in vitro growth of H37Rv in a MtbYM rich medium, by Himar1 transposon mutagenesis (see Minato et al. 2019). Non-essential gene for in vitro growth of H37Rv, by analysis of saturated Himar1 transposon libraries (see DeJesus et al. 2017). Non essential gene by Himar1 transposon mutagenesis in CDC1551 strain (see Lamichhane et al., 2003). Non-essential gene for in vitro growth of H37Rv, by Himar1 transposon mutagenesis (See Griffin et al., 2011).
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS20420012043272+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium tuberculosis H37Rv|Rv1801|PPE29
MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPSSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLIATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGAQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTFLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEFALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPIAATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPAMDD