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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionFunction unknown
ProductPPE family protein PPE30
CommentsRv1802, (MTV049.24), len: 463 aa. PPE30, Member of the Mycobacterium tuberculosis PPE family of glycine-rich proteins, most similar to AL022021|MTV049.30|Rv1809 (468 aa), FASTA scores: opt: 1238, E(): 0, (51.0% identity in 471 aa overlap).
Functional categoryPe/ppe
ProteomicsIdentified by mass spectrometry in M. tuberculosis H37Rv-infected guinea pig lungs at 30 and 90 days (See Kruh et al., 2010).
MutantNon-essential gene for in vitro growth of H37Rv, by analysis of saturated Himar1 transposon libraries (see DeJesus et al. 2017). Non-essential gene for in vitro growth of H37Rv, by Himar1 transposon mutagenesis (See Griffin et al., 2011).
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS20433842044775+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium tuberculosis H37Rv|Rv1802|PPE30
MDFGVLPPEINSGRMYAGPGSGPMLAAAAAWDGLATELQSTAADYGSVISVLTGVWSGQSSGTMAAAAAPYVAWMSATAALAREAAAQASAAAAAYEAAFAATVPPPVVAANRAELAVLAATNIFGQNTGAIAAAEARYAEMWAQDAAAMYGYAGSSSVATQVTPFAAPPPTTNAAGLATQGVAVAQAVGASAGNARSLVSEVLEFLATAGTNYNKTVASLMNAVTGVPYASSVYNSMLGLGFAESKMVLPANDTVISTIFGMVQFQKFFNPVTPFNPDLIPKSALGAGLGLRSAISSGLGSTAPAISAGASQAGSVGGMSVPPSWAAATPAIRTVAAVFSSTGLQAVPAAAISEGSLLSQMALASVAGGALGGAAARATGGFLGGGRVTAVKKSLKDSDSPDKLRRVVAHMMEKPESVQHWHTDEDGLDDLLAELKKKPGIHAVHMAGGNKAEIAPTISESG