Gene Rv2660c in Mycobacterium tuberculosis H37Rv
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameRv2660c
Gene length228 bp
IdentifierRv2660c
Location 2980963 bp
Protein summary information
Molecular mass7550.32 Da
Isoelectric point4.6292
Protein length75 amino acids
Orthologues
M. bovisMb2678c
Cross-references
UniProtI6Y1F5
TB databaseRv2660c
Interacting Drugs/Compounds
TDR TargetsLink
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductHypothetical protein
CommentsRv2660c, (MTCY441.29c), len: 75 aa (questionable orf). Hypothetical unknown protein.
Functional categoryConserved hypotheticals
TranscriptomicsmRNA identified by DNA microarray analysis: up-regulated at high temperatures, and highly up-regulated after 24h and 96h (very highly) of starvation (see citations below).
MutantNon-essential gene for in vitro growth of H37Rv in a MtbYM rich medium, by Himar1 transposon mutagenesis (see Minato et al. 2019). Non-essential gene for in vitro growth of H37Rv, by analysis of saturated Himar1 transposon libraries (see DeJesus et al. 2017). Found to be deleted (partially or completely) in one or more clinical isolates (See Tsolaki et al., 2004).
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29809632981190-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium tuberculosis H37Rv|Rv2660c|Rv2660c
VIAGVDQALAATGQASQRAAGASGGVTVGVGVGTEQRNLSVVAPSQFTFSSRSPDFVDETAGQSWCAILGLNQFH
Bibliography