Gene Rv3639c
in Mycobacterium tuberculosis H37Rv
General annotation
| Type | CDS |
| Function | Function unknown |
| Product | Conserved hypothetical protein |
| Comments | Rv3639c, (MTCY15C10.13), len: 188 aa. Hypothetical protein, with C-terminus highly similar to N-terminus of P95044|Rv0698|MTCY210.15 hypothetical 22.3 KDA protein from Mycobacterium tuberculosis (203 aa), FASTA scores: opt: 224, E(): 4.5e-07, (54.8% identity in 73 aa overlap). |
| Functional category | Conserved hypotheticals |
| Mutant | Non-essential gene for in vitro growth of H37Rv in a MtbYM rich medium, by Himar1 transposon mutagenesis (see Minato et al. 2019). Non-essential gene for in vitro growth of H37Rv, by analysis of saturated Himar1 transposon libraries (see DeJesus et al. 2017). Non essential gene by Himar1 transposon mutagenesis in H37Rv strain (see Sassetti et al., 2003). Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 4077884 | 4078450 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium tuberculosis H37Rv|Rv3639c|Rv3639c
MAGLFTPPASGAATLQRAARDAAPDARWLLAVSDRNGIVSTSATTCNYPPAAKDSAQDGFRHALAAAIAADIDEALRHGYGDLLELAYPLMSWPRRGVFGGPTPAPRGLATRQCPPRTVHVDRVRPNGAERALRARFRPILRPQFTLGDGANGLPLAACTKTGAYVPHLPYSPIAVDPQPSAGQQGPS
Bibliography
- Sassetti CM et al. [2003]. Genes required for mycobacterial growth defined by high density mutagenesis. Mutant
- Mazandu GK et al. [2012]. Function prediction and analysis of mycobacterium tuberculosis hypothetical proteins. Function
- DeJesus MA et al. [2017]. Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis. Mutant
- Minato Y et al. [2019]. Genomewide Assessment of Mycobacterium tuberculosis Conditionally Essential Metabolic Pathways. Mutant
