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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionFunction unknown; probably involved in cellular metabolism [catalytic activity: ATP + substrate = ADP + substrate 3'-phosphate].
ProductPossible phosphotransferase
CommentsRv3817, (MTCY409.13c), len: 251 aa. Possible phosphotransferase, similar to many phosphotransferases e.g. O53023 kanamycin marker from Escherichia coli (264 aa), FASTA scores: opt: 232, E(): 7.5e-08, (32.4% identity in 247 aa overlap); BAA78209|NEO neomycine phosphotransferase from Drosophila melanogaster (Fruit fly) (264 aa), FASTA scores: opt: 227, E(): 1.6e-07, (32.0% identity in 247 aa overlap); AAG09774 aminoglycoside 3'-phosphotransferase from Vibrio cholerae (264 aa), FASTA scores: opt: 227, E(): 1.6e-07, (32.0% identity in 247 aa overlap); P00552|KKA2_KLEPN|NEO|KAN aminoglycoside 3'-phosphotransferase from Klebsiella pneumoniae (264 aa), FASTA scores: opt: 227, E(): 1.6e-07, (32.0% identity in 247 aa overlap); etc.
Functional categoryIntermediary metabolism and respiration
ProteomicsTranslational start site supported by proteomics data (See Kelkar et al., 2011).
MutantNon-essential gene for in vitro growth of H37Rv, by analysis of saturated Himar1 transposon libraries (see DeJesus et al. 2017). Non essential gene by Himar1 transposon mutagenesis in H37Rv strain (see Sassetti et al., 2003). Non-essential gene for in vitro growth of H37Rv, by Himar1 transposon mutagenesis (See Griffin et al., 2011).
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS42816474282402+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium tuberculosis H37Rv|Rv3817|Rv3817
VSFPSSPPALPAIVARFAVGRPVRAVWVNELGGVTFRVDSGMGAGCEFIKVARRGTADFANEARRLRWAAPYLAVPRVLGVGVDGDWAWLHTDALPGLSAVHPRWRASPQVAVPALGAGLRTLHDSLPVHSCPFDWSTASRLAKLAPARRAELGDSPPVDRLVVCHGDACSPNTILDDTGRCCGHVDFGNLGVADRWADLAVATLSLQWNFPDYPGQVRDDEFFAAYGVAPDPARIDYYRRLWQAEDDSSR