Gene Rv3848
in Mycobacterium tuberculosis H37Rv
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Probable conserved transmembrane protein |
| Comments | Rv3848, (MTCY01A6.20c), len: 302 aa. Probable conserved transmembrane protein, similar to hypothetical (transmembrane) proteins e.g. Q9HVG2|PA4629 hypothetical protein from Pseudomonas aeruginosa (192 aa), FASTA scores: opt: 304, E(): 5.3e-11, (35.05% identity in 174 aa overlap); Q9A5S7|CC2370 hypothetical protein from Caulobacter crescentus (207 aa), FASTA scores: opt: 285, E(): 7.4e-10, (29.9% identity in 184 aa overlap); Q9KY43|SCC8A.05c putative integral membrane protein from Streptomyces coelicolor (193 aa), FASTA scores: opt: 245, E(): 1.6e-07, (32.8% identity in 195 aa overlap); etc. |
| Functional category | Cell wall and cell processes |
| Mutant | Non-essential gene for in vitro growth of H37Rv in a MtbYM rich medium, by Himar1 transposon mutagenesis (see Minato et al. 2019). Non-essential gene for in vitro growth of H37Rv, by analysis of saturated Himar1 transposon libraries (see DeJesus et al. 2017). Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 4322326 | 4323234 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium tuberculosis H37Rv|Rv3848|Rv3848
MLAATLLSLGAVFLAELGDRSQLITMTYTLRYRWWVVLTGVAIAAFTVHGVAVAIGHFLGSTVPARPAACVSAIAFLIFAVWVWREDTASDSETSPTAAEPRLALFTVVSSFALAELGDKTTLATVTLASDHHWAGVWIGTTLGMILADGLAIGAGLLLHRRLPERLLQVLTGLLFLLFGLWLLFDDALGFRSVAIAVTAAVVLAAATTAVSVRVAQTRRRRPTAAATPEDDSTRPERSSVAPGHPGSILLPLPEVSLRGRRPPSGSPDERCADPGSKGGSRRISVGCWLPGVGRIRPTRSS
Bibliography
- DeJesus MA et al. [2017]. Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis. Mutant
- Minato Y et al. [2019]. Genomewide Assessment of Mycobacterium tuberculosis Conditionally Essential Metabolic Pathways. Mutant
