Gene ML0378 (rimI)
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | probable acetyltransferase |
| Comments | ML0378, len: 359 aa. Probable acetyltransferase (EC 2.3.1.-). ML0378 appears to be a fusion of two M. tuberculosis homologues. In the C-terminus it is very similar to Rv3420c|Q50708|Z77165 rimI, probable ribosomal protein S18 acetyltransferase (158 aa), Fasta scores: E(): 0, (72.1% identity in 154 aa overlap); and in the N-terminus to Rv3421c|YY21_MYCTU|Q50707 conserved hypothetical protein (211 aa), Fasta scores: E(): 0, (75.6% identity in 205 aa overlap). Also similar to some other bacterial acetyltransferases and hypothetical proteins. Previously sequenced as YY21_MYCLE|Q49857 (359 aa), Fasta scores: E(): 0, (100.0% identity in 359 aa overlap). Contains Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family. |
| Functional category | Intermediary metabolism and respiration, Information pathways, Conserved hypotheticals |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 470765 | 471844 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0378|ML0378
MSIVLAIDTATAAVTAGIVAFDGHDCFTLAERVTVDAKAHVERLTPNVLVALADAELAMCELDAVVVGCGPGPFTGLRVGMATAAAYGHALGIPVHGVCSLDAIGVRTTGDTLVVTDARRHEVYWARYRDGVRIAGPAVGSPTDVDPGTALTVAGSPEHAALFGLPLCEPIYPTPAGLVAAVPDWSVSPIPLVALYLRRPDAKPITADNEPIVIGTLTPADVDRCAQLESQFFDGDNPWPAAAFDRELANSYNCYVGARTADTLVGYAGITRLGHTPPFEYEVHTIAVDPAYRGRGVGRRLLGELLDFAGSGAIYLEVRTDNETAIALYRSVGFERIGLRPRYYPASGADAYLMRREAQ
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