Gene ML0523 in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namenusB
Gene length573 bp
IdentifierML0523
Location 633534 bp
Protein summary information
Molecular mass20519.3 Da
Isoelectric point5.07
Protein length191 amino acids
Structural information
PFAMPF01029
Orthologs
M. tuberculosis H37RvRv2533c
M. lepromatosis Mx1-22AMLPM_0523
Cross-references
UniProtQ9CCR9
Gene OntologyRegulation of transcription, dna-dependent, Dna-dependent transcription, termination, Transcription termination factor activity, Rna binding
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductN utilization substance protein NusB (NusB protein)
CommentsML0523, len: 190 aa. nusB, N utilization substance protein, highly similar but longer to NUSB_MYCTU|P95020|Rv2533c nusB, putative transcription termination protein from M. tuberculosis (156 aa), Fasta scores: E(): 1e-43, (75.7% identity in 148 aa overlap); CAD94747|Mb2562c from M. bovis (156 aa). Also similar to many e.g. P54520|NUSB_BACSU from Bacillus subtilis (131 aa), FASTA scores: E(): 6.3e-15, (41.860% identity in 129 aa overlap); and NUSB_ECOLI|P04381 nusB, N utilization substance protein B from Escherichia coli (139 aa), Fasta scores: E(): 7.4e-08, (38.1% identity in 139 aa overlap). Contains Pfam match to entry PF01029 NusB, NusB family. Belongs to the NusB family.
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS633534634106+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML0523|nusB
MSNPVKGRHQARKRAVDLLFEAEARDLSPLEIIEVRSALAKSKLDVAPLHPYTVVVAQGVSEHTARIDELIISHLQGWKLDRLPAVDRAILRVSIWELLYADDVPEPVAVDEAVELAKELSTDDSPGFVNGLLGKVMLVTPQIRAAAQAVQQAVRMAAGTSEDHVPQREPAAGQLGQDDSNGGQVAAVCR
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