Gene ML0685c
in Mycobacterium leprae TN
General annotation
| Type | CDS |
| Function | Unknown |
| Product | Possible hydrolase |
| Comments | ML0685c, len: 303 aa. Possible hydrolase, highly similar to CAD95491|Mb3370 Conserved hypothetical protein from M. bovis (297 aa), fasta scores: opt: 1343, E(): 1.1e-83, (67.133% identity in 286 aa overlap) and highly similar at the N terminus to O53387|AL123456|Rv3337 conserved hypothetical protein from M. tuberculosis (82 aa), Fasta scores: E(): 2.8e-17, (74.3% identity in 70 aa overlap) and at the C terminus to O53388|AL123456|Rv3338 conserved hypothetical protein from M. tuberculosis (214 aa), Fasta scores: E(): 0, (65.9% identity in 214 aa overlap). Weakly similar to several hydrolases e.g. BAC74778|Q826V8 Putative hydrolase from Streptomyces avermitilis (307 aa), fasta scores: opt: 286, E(): 1e-11, (29.392% identity in 296 aa overlap). Previously sequenced as Q49926|U00022 (303 aa), Fasta scores: E(): 0, (99.7% identity in 303 aa overlap). Contains Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold. |
| Functional category | Intermediary metabolism and respiration, Conserved hypotheticals |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 821180 | 822091 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium leprae TN|ML0685c|ML0685c
VPACQHQRHRPVVACGTRGTTFRVGSMRQPIHLGSGEPVLLLHPFMMSQTVWEIVAPQLANTERYEVFAPTMAAHHGGPSASSWMMSVSTLADHVEQQLDELGWDTAHLVGNSLGGWVVFELERRGRARSVTGIAPAGGWTRWSLAKFEVIAKFVAGMPLVAVARGLGSRALSLPFSHRLASLPLTGSPAGLSEHQLRNIVEDAGHCPAYFLLLIKTLLQPGLRELADITVPVLLVLCEKDRVLPPPKYSRHFTDHLPERTQVTKFDGMGHVPMFEAPEVITKLITNFINQCSKPAEAASPAS
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