Gene ML1611c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namernhB
Gene length723 bp
IdentifierML1611c
Location 1935445 bp
Protein summary information
Molecular mass25599.6 Da
Isoelectric point9.1
Protein length241 amino acids
Structural information
PFAMPF01351
Orthologs
M. tuberculosis H37RvRv2902c
M. lepromatosis Mx1-22AMLPM_1611
Cross-references
UniProtO33022
Gene OntologyRna catabolic process, Cytoplasm, Manganese ion binding, Ribonuclease h activity, Rna binding
Enzyme Classification3.1.26.4
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE RIBONUCLEASE HII PROTEIN RNHB (RNASE HII)
CommentsML1611c, len: 240 aa. Probable rnhB, ribonuclease HII protein (EC 3.1.26.4). Highly similar to many ribonucleases including: Brucella melitensis ribonuclease HII and Mycobacterium tuberculosis ribonuclease HII Rv2902c SW:RNH2_MYCTU (Q10793) (264 aa), Fasta scores: E(): 0, 76.7% identity in 245 aa overlap. Contains Pfam match to entry PF01351 RNase_HII, Ribonuclease HII. Contains PS00017 ATP/GTP-binding site motif A (P-loop).
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS19354451936167-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1611c|rnhB
MATTWPPCRIIRKSGGLRGMWTLEYELQRSGLGPVAGVDEVGRGACAGPLVVAACVLGPGRLEESLDDSKKLSAKGREMLFPLICRYALAYHVVFIPSVEVDRHGVQVANIEGMRRAVAGLSVRPGYVLSDGFRVPGLSVPSLPVVGGDAVVACIAAASVLAKVSRDRLMVAMDADYPGYGFAAHKGYCTRAHSLALTQLGPCPEHRYSFINVRRIVTRSNTRAVAGFTPAPPAEHGECR
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