Gene ML1955c in Mycobacterium leprae TN
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nametruA
Gene length750 bp
IdentifierML1955c
Location 2343336 bp
Protein summary information
Molecular mass27835.6 Da
Isoelectric point9.54
Protein length250 amino acids
Structural information
PFAMPF01416
Orthologs
M. tuberculosis H37RvRv3455c
M. lepromatosis Mx1-22AMLPM_1955
Cross-references
UniProtQ9X796
Gene OntologyTrna pseudouridine synthesis, Pseudouridine synthase activity
Enzyme Classification5.4.99.12
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE TRNA PSEUDOURIDINE SYNTHASE A TRUA (PSEUDOURIDYLATE SYNTHASE I) (PSEUDOURIDINE SYNTHASE I) (URACIL HYDROLYASE)
CommentsML1955c, len: 249 aa. Probable truA, tRNA pseudouridine synthase A (EC 4.2.1.70). Similar to M. tuberculosis probable pseudouridylate synthase truA Rv3455c SW:TRUA_MYCTU (Z95390) (256 aa), Fasta scores: E(): 0, 77.2% identity in 246 aa overlap, and to many others e.g Pseudomonas aeruginosa tRNA pseudouridine synthase A SW:TRUA_PSEAE (O87016) (285 aa), Fasta scores: E(): 4.2e-16, 34.3% identity in 242 aa overlap. Contains Pfam match to entry PF01416 PseudoU_synth_1, tRNA pseudouridine synthase.
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS23433362344085-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium leprae TN|ML1955c|truA
VLDEAFTTVFRTPVRLRAAGRTDTGVHATGQVAHVDIPGTALSKANPRSPHTGDPEFLPLLRRLSRLLPVDVRVLDIACAPVGFDARFSALRRHYRYRLSTAPYGVQPNQARYVTAWPRELDLDSMSAASRDLLGLRDFAVFCRHRHGATTIRELQRLEWSREGYLITAHITADAFCWSMVRSLIGALLAVGDHRRTIGWCGELLTKASRSSDFTTAPAHGLTFIRVDYPPDDELAERAVITRDLRSSF
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